Modulating the enterohepatic circulation in cholestatic and metabolic liver diseases: Therapeutic perspectives

Bile salts are synthesized in the liver and temporarily stored in the gall bladder, before they are released in the small intestine upon food intake. Here, they help with the digestion and absorption of food and nutrients. The enterohepatic circulation is the circulation of bile salts from the liver to the gall bladder, the small intestine and back to the liver via the portal vein. The enterohepatic