Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells

E. Giovannetti; C. Lemos; C. Tekle; K Smid; S. Nannizzi; J.A. Rodriguez; S. Ricciardi; R. Danesi; G. Giaccone; G.J. Peters

doi:https://doi.org/10.1124/mol.107.042382

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells

E. Giovannetti, C. Lemos, C. Tekle, K Smid, S. Nannizzi, J.A. Rodriguez, S. Ricciardi, R. Danesi, G. Giaccone, G.J. Peters

Research output: Contribution to journal › Article › Academic › peer-review

146 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	1290-1300
Journal	Molecular pharmacology
Volume	73
Issue number	4
DOIs	https://doi.org/10.1124/mol.107.042382
Publication status	Published - 2008

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https://doi.org/10.1124/mol.107.042382

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Giovannetti, E., Lemos, C., Tekle, C., Smid, K., Nannizzi, S., Rodriguez, J. A., Ricciardi, S., Danesi, R., Giaccone, G., & Peters, G. J. (2008). Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells. Molecular pharmacology, 73(4), 1290-1300. https://doi.org/10.1124/mol.107.042382

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author = "E. Giovannetti and C. Lemos and C. Tekle and K Smid and S. Nannizzi and J.A. Rodriguez and S. Ricciardi and R. Danesi and G. Giaccone and G.J. Peters",

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Giovannetti, E, Lemos, C, Tekle, C, Smid, K, Nannizzi, S, Rodriguez, JA, Ricciardi, S, Danesi, R, Giaccone, G & Peters, GJ 2008, 'Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells', Molecular pharmacology, vol. 73, no. 4, pp. 1290-1300. https://doi.org/10.1124/mol.107.042382

Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells. / Giovannetti, E.; Lemos, C.; Tekle, C. et al.
In: Molecular pharmacology, Vol. 73, No. 4, 2008, p. 1290-1300.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Giovannetti, E.

AU - Lemos, C.

AU - Tekle, C.

AU - Smid, K

AU - Nannizzi, S.

AU - Rodriguez, J.A.

AU - Ricciardi, S.

AU - Danesi, R.

AU - Giaccone, G.

AU - Peters, G.J.

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Giovannetti E, Lemos C, Tekle C, Smid K, Nannizzi S, Rodriguez JA et al. Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells. Molecular pharmacology. 2008;73(4):1290-1300. doi: https://doi.org/10.1124/mol.107.042382