Multiparametric MRI in a patient with adult-onset leukoencephalopathy with vanishing white matter

A. Gallo; M. A. Rocca; A. Falini; C. Scaglione; F. Salvi; A. Gambini; L. Guerrini; M. Mascalchi; J. C. Pronk; M. S. Van Der Knaap; Massimo Filippi

doi:https://doi.org/10.1212/01.WNL.0000103292.72400.B7

Multiparametric MRI in a patient with adult-onset leukoencephalopathy with vanishing white matter

A. Gallo, M. A. Rocca, A. Falini, C. Scaglione, F. Salvi, A. Gambini, L. Guerrini, M. Mascalchi, J. C. Pronk, M. S. Van Der Knaap, Massimo Filippi

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

Abstract

This is a multiparametric MR study of the first reported patient with adult-onset genetically confirmed vanishing white matter (VWM) disease. It shows that, despite the presence of a severe and diffuse damage of the brain WM, brain gray matter, and cervical cord tissue, the cortical adaptive capacities were relatively preserved. Interpatient variability of brain plasticity may contribute to the known phenotypic variation of patients with VWM disease.

Original language	English
Pages (from-to)	323-326
Number of pages	4
Journal	Neurology
Volume	62
Issue number	2
DOIs	https://doi.org/10.1212/01.WNL.0000103292.72400.B7
Publication status	Published - 27 Jan 2004

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abstract = "This is a multiparametric MR study of the first reported patient with adult-onset genetically confirmed vanishing white matter (VWM) disease. It shows that, despite the presence of a severe and diffuse damage of the brain WM, brain gray matter, and cervical cord tissue, the cortical adaptive capacities were relatively preserved. Interpatient variability of brain plasticity may contribute to the known phenotypic variation of patients with VWM disease.",

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AU - Gallo, A.

AU - Rocca, M. A.

AU - Falini, A.

AU - Scaglione, C.

AU - Salvi, F.

AU - Gambini, A.

AU - Guerrini, L.

AU - Mascalchi, M.

AU - Pronk, J. C.

AU - Van Der Knaap, M. S.

AU - Filippi, Massimo

PY - 2004/1/27

Y1 - 2004/1/27

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AB - This is a multiparametric MR study of the first reported patient with adult-onset genetically confirmed vanishing white matter (VWM) disease. It shows that, despite the presence of a severe and diffuse damage of the brain WM, brain gray matter, and cervical cord tissue, the cortical adaptive capacities were relatively preserved. Interpatient variability of brain plasticity may contribute to the known phenotypic variation of patients with VWM disease.

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Multiparametric MRI in a patient with adult-onset leukoencephalopathy with vanishing white matter

Abstract

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