TY - JOUR
T1 - Multiscale network neuroscience in neuro-oncology
T2 - How tumors, brain networks, and behavior connect across scales
AU - Maas, Dorien A.
AU - Douw, Linda
N1 - Funding Information: LD is sponsored by a Vidi grant (NWO 198.015). Publisher Copyright: © The Author(s) 2023. Published by Oxford University Press on behalf of the Society for Neuro-Oncology and the European Association of Neuro-Oncology.
PY - 2023/12/1
Y1 - 2023/12/1
N2 - Network neuroscience refers to the investigation of brain networks across different spatial and temporal scales, and has become a leading framework to understand the biology and functioning of the brain. In neuro-oncology, the study of brain networks has revealed many insights into the structure and function of cells, circuits, and the entire brain, and their association with both functional status (e.g., cognition) and survival. This review connects network findings from different scales of investigation, with the combined aim of informing neuro-oncological healthcare professionals on this exciting new field and also delineating the promising avenues for future translational and clinical research that may allow for application of network methods in neuro-oncological care.
AB - Network neuroscience refers to the investigation of brain networks across different spatial and temporal scales, and has become a leading framework to understand the biology and functioning of the brain. In neuro-oncology, the study of brain networks has revealed many insights into the structure and function of cells, circuits, and the entire brain, and their association with both functional status (e.g., cognition) and survival. This review connects network findings from different scales of investigation, with the combined aim of informing neuro-oncological healthcare professionals on this exciting new field and also delineating the promising avenues for future translational and clinical research that may allow for application of network methods in neuro-oncological care.
KW - connectome
KW - functional connectivity
KW - glioma
KW - graph theory
KW - structural connectivity
UR - http://www.scopus.com/inward/record.url?scp=85178557052&partnerID=8YFLogxK
U2 - https://doi.org/10.1093/nop/npad044
DO - https://doi.org/10.1093/nop/npad044
M3 - Review article
C2 - 38026586
SN - 2054-2577
VL - 10
SP - 506
EP - 517
JO - Neuro-Oncology Practice
JF - Neuro-Oncology Practice
IS - 6
ER -