TY - JOUR
T1 - Mumps: Not an Innocent Bystander in Solid Organ Transplantation
AU - Baas, M. C.
AU - van Donselaar, K. A. M. I.
AU - Florquin, S.
AU - van Binnendijk, R. S.
AU - ten Berge, I. J. M.
AU - Bemelman, F. J.
PY - 2009
Y1 - 2009
N2 - Recently two major outbreaks of mumps have occurred: in the UK more than 56,000 cases were notified between 2004 and 2005, and in the United States, 6,584 cases were reported in 2006. Most patients were young healthy adults, in whom mumps normally has a benign course. Little is known about mumps in the immunocompromised patient. Here, we report a case of a 56-year renal transplant recipient who developed acute irreversible transplant failure due to interstitial nephritis caused by mumps. RNA of the mumps virus was detected in the urine as well as in a renal biopsy. In view of the ongoing presence of the mumps virus in the population, one should be aware of the possible occurrence of this infection in immunocompromised patients
AB - Recently two major outbreaks of mumps have occurred: in the UK more than 56,000 cases were notified between 2004 and 2005, and in the United States, 6,584 cases were reported in 2006. Most patients were young healthy adults, in whom mumps normally has a benign course. Little is known about mumps in the immunocompromised patient. Here, we report a case of a 56-year renal transplant recipient who developed acute irreversible transplant failure due to interstitial nephritis caused by mumps. RNA of the mumps virus was detected in the urine as well as in a renal biopsy. In view of the ongoing presence of the mumps virus in the population, one should be aware of the possible occurrence of this infection in immunocompromised patients
U2 - https://doi.org/10.1111/j.1600-6143.2009.02732.x
DO - https://doi.org/10.1111/j.1600-6143.2009.02732.x
M3 - Article
C2 - 19563333
SN - 1600-6135
VL - 9
SP - 2186
EP - 2189
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 9
ER -