NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?

L Van Heerebeek; C Meischl; W Stooker; C J L M Meijer; H W M Niessen; D Roos

doi:https://doi.org/10.1136/jcp.55.8.561

NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?

L Van Heerebeek, C Meischl, W Stooker, C J L M Meijer, H W M Niessen, D Roos

Research output: Contribution to journal › Review article › Academic › peer-review

85 Citations (Scopus)

Abstract

Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.

Original language	English
Pages (from-to)	561-8
Number of pages	8
Journal	Journal of clinical pathology
Volume	55
Issue number	8
DOIs	https://doi.org/10.1136/jcp.55.8.561
Publication status	Published - Aug 2002

Keywords

Animals
Blood Vessels
Humans
Journal Article
Muscle, Smooth, Vascular
NADH, NADPH Oxidoreductases
Reactive Oxygen Species
Research Support, Non-U.S. Gov't
Review
Signal Transduction

Access to Document

https://doi.org/10.1136/jcp.55.8.561

Cite this

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title = "NADPH oxidase(s): new source(s) of reactive oxygen species in the vascular system?",

abstract = "Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.",

keywords = "Animals, Blood Vessels, Humans, Journal Article, Muscle, Smooth, Vascular, NADH, NADPH Oxidoreductases, Reactive Oxygen Species, Research Support, Non-U.S. Gov't, Review, Signal Transduction",

author = "{Van Heerebeek}, L and C Meischl and W Stooker and Meijer, {C J L M} and Niessen, {H W M} and D Roos",

year = "2002",

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language = "English",

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journal = "Journal of clinical pathology",

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T2 - new source(s) of reactive oxygen species in the vascular system?

AU - Van Heerebeek, L

AU - Meischl, C

AU - Stooker, W

AU - Meijer, C J L M

AU - Niessen, H W M

AU - Roos, D

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AB - Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.

KW - Animals

KW - Blood Vessels

KW - Humans

KW - Journal Article

KW - Muscle, Smooth, Vascular

KW - NADH, NADPH Oxidoreductases

KW - Reactive Oxygen Species

KW - Research Support, Non-U.S. Gov't

KW - Review

KW - Signal Transduction

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DO - https://doi.org/10.1136/jcp.55.8.561

M3 - Review article

C2 - 12147646

SN - 0021-9746

VL - 55

SP - 561

EP - 568

JO - Journal of clinical pathology

JF - Journal of clinical pathology

IS - 8

ER -