Neoangiogenesis in the peritoneal membrane

R. T. Krediet; M. M. Zweers; A. C. van der Wal; D. G. Struijk

Neoangiogenesis in the peritoneal membrane

R. T. Krediet, M. M. Zweers, A. C. van der Wal, D. G. Struijk

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Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

OBJECTIVE: This study reviews relevant publications on the peritoneal vasculature and tries to establish morphological-functional relationships. DESIGN: The design is a review article. RESULTS: Recent morphological studies in peritoneal dialysis (PD) patients have shown the presence of diabetiform neoangiogenesis in long-term peritoneal dialysis. The same abnormalities could be induced in rats administered a high glucose dialysis solution daily for 20 weeks. The animals showed functional abnormalities in peritoneal transport similar to those found in long-term PD patients. Evidence was obtained in patients that vascular endothelial growth factor could be involved in glucose-induced peritoneal neoangiogenesis. CONCLUSIONS: Diabetiform peritoneal neoangiogenesis is an important pathogenetic factor in ultrafiltration failure in long-term peritoneal dialysis patients

Original language	English
Pages (from-to)	S19-S25
Journal	Peritoneal Dialysis International
Volume	20
Issue number	Suppl. 2
Publication status	Published - 2000

Cite this

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title = "Neoangiogenesis in the peritoneal membrane",

abstract = "OBJECTIVE: This study reviews relevant publications on the peritoneal vasculature and tries to establish morphological-functional relationships. DESIGN: The design is a review article. RESULTS: Recent morphological studies in peritoneal dialysis (PD) patients have shown the presence of diabetiform neoangiogenesis in long-term peritoneal dialysis. The same abnormalities could be induced in rats administered a high glucose dialysis solution daily for 20 weeks. The animals showed functional abnormalities in peritoneal transport similar to those found in long-term PD patients. Evidence was obtained in patients that vascular endothelial growth factor could be involved in glucose-induced peritoneal neoangiogenesis. CONCLUSIONS: Diabetiform peritoneal neoangiogenesis is an important pathogenetic factor in ultrafiltration failure in long-term peritoneal dialysis patients",

author = "Krediet, {R. T.} and Zweers, {M. M.} and {van der Wal}, {A. C.} and Struijk, {D. G.}",

year = "2000",

language = "English",

volume = "20",

pages = "S19--S25",

journal = "Peritoneal Dialysis International",

issn = "0896-8608",

publisher = "Multimed Inc.",

number = "Suppl. 2",

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TY - JOUR

T1 - Neoangiogenesis in the peritoneal membrane

AU - Krediet, R. T.

AU - Zweers, M. M.

AU - van der Wal, A. C.

AU - Struijk, D. G.

PY - 2000

Y1 - 2000

N2 - OBJECTIVE: This study reviews relevant publications on the peritoneal vasculature and tries to establish morphological-functional relationships. DESIGN: The design is a review article. RESULTS: Recent morphological studies in peritoneal dialysis (PD) patients have shown the presence of diabetiform neoangiogenesis in long-term peritoneal dialysis. The same abnormalities could be induced in rats administered a high glucose dialysis solution daily for 20 weeks. The animals showed functional abnormalities in peritoneal transport similar to those found in long-term PD patients. Evidence was obtained in patients that vascular endothelial growth factor could be involved in glucose-induced peritoneal neoangiogenesis. CONCLUSIONS: Diabetiform peritoneal neoangiogenesis is an important pathogenetic factor in ultrafiltration failure in long-term peritoneal dialysis patients

AB - OBJECTIVE: This study reviews relevant publications on the peritoneal vasculature and tries to establish morphological-functional relationships. DESIGN: The design is a review article. RESULTS: Recent morphological studies in peritoneal dialysis (PD) patients have shown the presence of diabetiform neoangiogenesis in long-term peritoneal dialysis. The same abnormalities could be induced in rats administered a high glucose dialysis solution daily for 20 weeks. The animals showed functional abnormalities in peritoneal transport similar to those found in long-term PD patients. Evidence was obtained in patients that vascular endothelial growth factor could be involved in glucose-induced peritoneal neoangiogenesis. CONCLUSIONS: Diabetiform peritoneal neoangiogenesis is an important pathogenetic factor in ultrafiltration failure in long-term peritoneal dialysis patients

M3 - Article

C2 - 10911638

SN - 0896-8608

VL - 20

SP - S19-S25

JO - Peritoneal Dialysis International

JF - Peritoneal Dialysis International

IS - Suppl. 2

ER -