TY - JOUR
T1 - Neovaginal cancer after sigmoid vaginoplasty
T2 - Implications for postoperative cancer surveillance
AU - van der Sluis, Wouter B.
AU - de Boer, Nanne K. H.
AU - Buncamper, Marlon E.
AU - van Bodegraven, Adriaan A.
AU - Tuynman, Jurriaan B.
AU - Bouman, Mark-Bram
N1 - Publisher Copyright: © 2024 The Author(s)
PY - 2024/6/1
Y1 - 2024/6/1
N2 - Background: Intestinal vaginoplasty can be performed as vaginal reconstruction procedure. Aa pedicled intestinal segment is isolated and transferred to the (neo)vaginal cavity to form the neovaginal lining. Case: A 38-year old patient with Fanconi anemia and congenital vaginal absence, who underwent sigmoid vaginoplasty at the age of one, visited the outpatient clinic with a palpable neovaginal mass. At MRI examination, a neovaginal tumor was observed of approximately 25 × 10 mm without lymphadenopathy, which turned out to be a mucinous adenocarcinoma (T3N0M0). She underwent excision of the total mesocolon, including the sigmoid neovagina, coloanal anastomosis and anus. Summary and Conclusion: Postoperative cancer surveillance seems justified after sigmoid vaginoplasty, even more so in patients with a (genetically) high risk of developing cancer and/or with a history of malignancy.
AB - Background: Intestinal vaginoplasty can be performed as vaginal reconstruction procedure. Aa pedicled intestinal segment is isolated and transferred to the (neo)vaginal cavity to form the neovaginal lining. Case: A 38-year old patient with Fanconi anemia and congenital vaginal absence, who underwent sigmoid vaginoplasty at the age of one, visited the outpatient clinic with a palpable neovaginal mass. At MRI examination, a neovaginal tumor was observed of approximately 25 × 10 mm without lymphadenopathy, which turned out to be a mucinous adenocarcinoma (T3N0M0). She underwent excision of the total mesocolon, including the sigmoid neovagina, coloanal anastomosis and anus. Summary and Conclusion: Postoperative cancer surveillance seems justified after sigmoid vaginoplasty, even more so in patients with a (genetically) high risk of developing cancer and/or with a history of malignancy.
KW - Cancer
KW - Intestinal vaginoplasty
KW - Neovagina
KW - Sigmoid vaginoplasty
KW - Transgender
UR - http://www.scopus.com/inward/record.url?scp=85188506928&partnerID=8YFLogxK
U2 - 10.1016/j.jpra.2024.03.002
DO - 10.1016/j.jpra.2024.03.002
M3 - Article
C2 - 38544675
SN - 2352-5878
VL - 40
SP - 170
EP - 174
JO - JPRAS Open
JF - JPRAS Open
ER -