TY - JOUR
T1 - New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity
AU - Fineberg, Naomi A.
AU - Chamberlain, Samuel R.
AU - Goudriaan, Anna E.
AU - Stein, Dan J.
AU - Vanderschuren, Louk J. M. J.
AU - Gillan, Claire M.
AU - Shekar, Sameer
AU - Gorwood, Philip A. P. M.
AU - Voon, Valerie
AU - Morein-Zamir, Sharon
AU - Denys, Damiaan
AU - Sahakian, Barbara J.
AU - Moeller, F. Gerard
AU - Robbins, Trevor W.
AU - Potenza, Marc N.
PY - 2014
Y1 - 2014
N2 - Impulsivity and compulsivity represent useful conceptualizations that involve dissociable cognitive functions, which are mediated by neuroanatomically and neurochemically distinct components of cortico-subcortical circuitry. The constructs were historically viewed as diametrically opposed, with impulsivity being associated with risk-seeking and compulsivity with harm-avoidance. However, they are increasingly recognized to be linked by shared neuropsychological mechanisms involving dysfunctional inhibition of thoughts and behaviors. In this article, we selectively review new developments in the investigation of the neurocognition of impulsivity and compulsivity in humans, in order to advance our understanding of the pathophysiology of impulsive, compulsive, and addictive disorders and indicate new directions for research
AB - Impulsivity and compulsivity represent useful conceptualizations that involve dissociable cognitive functions, which are mediated by neuroanatomically and neurochemically distinct components of cortico-subcortical circuitry. The constructs were historically viewed as diametrically opposed, with impulsivity being associated with risk-seeking and compulsivity with harm-avoidance. However, they are increasingly recognized to be linked by shared neuropsychological mechanisms involving dysfunctional inhibition of thoughts and behaviors. In this article, we selectively review new developments in the investigation of the neurocognition of impulsivity and compulsivity in humans, in order to advance our understanding of the pathophysiology of impulsive, compulsive, and addictive disorders and indicate new directions for research
U2 - https://doi.org/10.1017/S1092852913000801
DO - https://doi.org/10.1017/S1092852913000801
M3 - Review article
C2 - 24512640
SN - 1092-8529
VL - 19
SP - 69
EP - 89
JO - CNS spectrums
JF - CNS spectrums
IS - 1
ER -