TY - JOUR
T1 - Non-immune hydrops fetalis: A short review of etiology and pathophysiology
AU - Bellini, Carlo
AU - Hennekam, Raoul C. M.
PY - 2012
Y1 - 2012
N2 - Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non-immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non-immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow-chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. (c) 2012 Wiley Periodicals, Inc
AB - Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non-immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non-immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow-chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. (c) 2012 Wiley Periodicals, Inc
U2 - https://doi.org/10.1002/ajmg.a.34438
DO - https://doi.org/10.1002/ajmg.a.34438
M3 - Review article
C2 - 22302731
SN - 1552-4825
VL - 158A
SP - 597
EP - 605
JO - American journal of medical genetics. Part A
JF - American journal of medical genetics. Part A
IS - 3
ER -