Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne Muscular Dystrophy: A case report

Justus Martijn Brinkman; Jorg R. Oddens; Barend J. Van Royen; Jan Wever; Jan G. Olsman

doi:https://doi.org/10.1186/1471-2482-4-1

Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne Muscular Dystrophy: A case report

Justus Martijn Brinkman, Jorg R. Oddens, Barend J. Van Royen, Jan Wever, Jan G. Olsman

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Background: Clinical characteristics and complications of Duchenne muscular dystrophy caused by skeletal and cardiac muscle degeneration are well known. Gastro-intestinal involvement has also been recognised in these patients. However an acute perforated gastro-duodenal peptic ulcer has not been documented up to now. Case presentation: A 26-year-old male with Duchenne muscular dystrophy with a clinical and radiographic diagnosis of acute perforated gastro-duodenal peptic ulcer is treated non-operatively with naso-gastric suction and intravenous medication. Gastrointestinal involvement in Duchenne muscular dystrophy and therapeutic considerations in a high risk patient are discussed. Conclusion: Non-surgical treatment for perforated gastro-duodenal peptic ulcer should be considered in high risk patients, as is the case in patients with Duchenne muscular dystrophy. Patients must be carefully observed and operated on if non-operative treatment is unsuccessful.

Original language	English
Article number	1
Pages (from-to)	1-5
Number of pages	5
Journal	BMC Surgery
Volume	4
DOIs	https://doi.org/10.1186/1471-2482-4-1
Publication status	Published - 8 Jan 2004

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title = "Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne Muscular Dystrophy: A case report",

abstract = "Background: Clinical characteristics and complications of Duchenne muscular dystrophy caused by skeletal and cardiac muscle degeneration are well known. Gastro-intestinal involvement has also been recognised in these patients. However an acute perforated gastro-duodenal peptic ulcer has not been documented up to now. Case presentation: A 26-year-old male with Duchenne muscular dystrophy with a clinical and radiographic diagnosis of acute perforated gastro-duodenal peptic ulcer is treated non-operatively with naso-gastric suction and intravenous medication. Gastrointestinal involvement in Duchenne muscular dystrophy and therapeutic considerations in a high risk patient are discussed. Conclusion: Non-surgical treatment for perforated gastro-duodenal peptic ulcer should be considered in high risk patients, as is the case in patients with Duchenne muscular dystrophy. Patients must be carefully observed and operated on if non-operative treatment is unsuccessful.",

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AU - Brinkman, Justus Martijn

AU - Oddens, Jorg R.

AU - Van Royen, Barend J.

AU - Wever, Jan

AU - Olsman, Jan G.

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AB - Background: Clinical characteristics and complications of Duchenne muscular dystrophy caused by skeletal and cardiac muscle degeneration are well known. Gastro-intestinal involvement has also been recognised in these patients. However an acute perforated gastro-duodenal peptic ulcer has not been documented up to now. Case presentation: A 26-year-old male with Duchenne muscular dystrophy with a clinical and radiographic diagnosis of acute perforated gastro-duodenal peptic ulcer is treated non-operatively with naso-gastric suction and intravenous medication. Gastrointestinal involvement in Duchenne muscular dystrophy and therapeutic considerations in a high risk patient are discussed. Conclusion: Non-surgical treatment for perforated gastro-duodenal peptic ulcer should be considered in high risk patients, as is the case in patients with Duchenne muscular dystrophy. Patients must be carefully observed and operated on if non-operative treatment is unsuccessful.

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Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne Muscular Dystrophy: A case report

Abstract

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