TY - JOUR
T1 - Nutritional management of patients with acute pancreatitis: a Dutch observational multicentre study
AU - Spanier, B. W. M.
AU - Mathus-Vliegen, E. M. H.
AU - Tuynman, H. A. R. E.
AU - van der Hulst, R. W. M.
AU - Dijkgraaf, M. G. W.
AU - Bruno, M. J.
AU - AUTHOR GROUP
AU - van Bodegraven, A. A.
AU - Wesdorp, I. C. E.
AU - van Heukelem, H. A.
AU - Geraerdts, A. A.
AU - Teunen, A.
AU - Noach, L. A.
AU - Slot, W. Bruins
AU - de Groot, G. H.
AU - Loffeld, R. J. L. F.
AU - Viergever, P. P.
AU - Klemt, M.
AU - Oosting, P. R.
AU - Wagtmans, M. J.
AU - Kingma, P. J.
AU - Ponsioen, C. Y.
PY - 2008
Y1 - 2008
N2 - Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. To evaluate the nutritional management of patients with AP in a Dutch cohort (EARL study). Observational study in 18 hospitals. Total days of NPO, tube feeding (TF) with/without oral feeding, total parenteral nutrition (TPN) and total starvation time were analysed. In mild AP, a majority of cases (80.7%, 117/145) were managed with an NPO regimen only. Twenty-seven patients (18.6%) with mild AP additionally received TF; one received TPN. Of those with severe AP, more than half of the patients (56.2%, nine of 16) were treated with TF besides an NPO regimen; four received TPN. TF was delivered preferably via the jejunal route. The median period of total starvation was 2 days for both mild and severe AP. Only 5.5% (nine of 164) of patients had a prolonged starvation time of more than 5 days. The total time of starvation was limited in a majority of patients admitted for AP. According to international guidelines, additional nutritional interventions were quickly undertaken with enteral feeding via the jejunum as the preferred route
AB - Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. To evaluate the nutritional management of patients with AP in a Dutch cohort (EARL study). Observational study in 18 hospitals. Total days of NPO, tube feeding (TF) with/without oral feeding, total parenteral nutrition (TPN) and total starvation time were analysed. In mild AP, a majority of cases (80.7%, 117/145) were managed with an NPO regimen only. Twenty-seven patients (18.6%) with mild AP additionally received TF; one received TPN. Of those with severe AP, more than half of the patients (56.2%, nine of 16) were treated with TF besides an NPO regimen; four received TPN. TF was delivered preferably via the jejunal route. The median period of total starvation was 2 days for both mild and severe AP. Only 5.5% (nine of 164) of patients had a prolonged starvation time of more than 5 days. The total time of starvation was limited in a majority of patients admitted for AP. According to international guidelines, additional nutritional interventions were quickly undertaken with enteral feeding via the jejunum as the preferred route
U2 - https://doi.org/10.1111/j.1365-2036.2008.03814.x
DO - https://doi.org/10.1111/j.1365-2036.2008.03814.x
M3 - Article
C2 - 18657130
SN - 0269-2813
VL - 28
SP - 1159
EP - 1165
JO - Alimentary pharmacology & therapeutics
JF - Alimentary pharmacology & therapeutics
IS - 9
ER -