Abstract
Original language | English |
---|---|
Pages (from-to) | 263-274 |
Number of pages | 12 |
Journal | Contact dermatitis |
Volume | 88 |
Issue number | 4 |
Early online date | 2023 |
DOIs | |
Publication status | Published - Apr 2023 |
Keywords
- RRID:SCR_001905
- baseline series
- clinical epidemiology
- occupational contact allergy
- patch testing
- surveillance
Access to Document
Other files and links
Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver
}
In: Contact dermatitis, Vol. 88, No. 4, 04.2023, p. 263-274.
Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Occupational contact allergy
T2 - The European perspective–Analysis of patch test data from ESSCA between 2011 and 2020
AU - Bauer, Andrea
AU - Pesonen, Maria
AU - Brans, Richard
AU - Caroppo, Francesca
AU - Dickel, Heinrich
AU - Dugonik, Aleksandra
AU - Larese Filon, Francesca
AU - Geier, Johannes
AU - Gimenez-Arnau, Ana M.
AU - Napolitano, Maddalena
AU - Patruno, Cataldo
AU - Rustemeyer, Thomas
AU - Simon, Dagmar
AU - Schuttelaar, Marie L. A.
AU - Spiewak, Radoslaw
AU - Stingeni, Luca
AU - Vok, Marko
AU - Weisshaar, Elke
AU - Wilkinson, Mark
AU - Valiukeviciene, Skaidra
AU - Uter, Wolfgang
N1 - Funding Information: Partial funding by EADV Grant PPRC‐2018‐8. Open access publication was funded by DEAL agreement. Funding Information: Birger Kränke, Department of Dermatology, Medical University of Graz, Graz, Austria, Graz, Austria (birger.kraenke@medunigraz.at); Kathrin Scherer Hofreiter, Department of Dermatology, Allergy Unit, University Hospital Basel, Basel, Switzerland (kathrin.scherer@usb.ch); Alexander Navarini, NA, Basel, Switzerland (alexander.navarini@usb.ch); Jürgen Grabbe, Department of Dermatology, Kantonsspital Aarau, Aarau, Switzerland (juergen.grabbe@ksa.ch); Philip Spring, Dermatologie et vénéréologie FMH, Center Médical d'Epalinges, Lausanne/Epalignes, Switzerland (springphil@hotmail.com); Ulrike Beiteke, Department of Dermatology, Dortmund, Germany (ulrike.beiteke@klinikumdo.de); Timo Buhl, Department of Dermatology, University Medicine, Göttingen, Germany (timo.buhl@med.uni-goettingen.de); Cecilia Dietrich, Department of Dermatology, University of Schleswig-Holstein, Campus Kiel, Kiel, Germany (cdietrich@dermatology.uni-kiel.de); Sibylle Schliemann, Department of Dermatology and Allergology, University Hospital Jena, Jena, Germany (schliemann@derma-jena.de); Detlef Becker, Department of Dermatology, University of Mainz, Mainz, Germany (detlef.becker@unimedizin-mainz.de); Swen Malte John, Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), University of Osnabrück, Lower Saxony Institute for Occupational Dermatology (NIB), Osnabrück, Germany (sjohn@uni-osnabrueck.de); Nicola Wagner, Department of Dermatology, University of Erlangen-Nürnberg, Erlangen, Germany (nicola.wagner@uk-erlangen.de); Thomas Werfel, Medizinische Hochschule Hannover, Department of Immunodermatology and experimental Allergy, Hannover, Germany (werfel.thomas@mh-hannover.de); Javier Sánchez-Pérez, Department of Dermatology, Hospital Universitario la Princesa, Madrid/Princesa, Spain (jsanchezperez@aedv.es); Juan Fco. Silvestre, Department of Dermatology, Hospital General Universitario de Alicante, Alicante, Spain (silvestre_jfr@gva.es); José C. Amario-Hita, Department of Dermatology, University Hospital of Puerto Real, Cádiz, Spain (jcarmarioh@gmail.com); Pedro Mercader, Dermatology Department, Hospital General Universitario Morales Meseguer, Murcia, Spain (pedromercader@hotmail.com); Inmaculada Ruiz, Department of Dermatology, Complejo Asistencial de León, C/Altos de Nava s/n, León, Spain (iruizgon@saludcastillayleon.es); Juan García-Gavín, Clínica Pérez & Gavín dermalogos, Vigo, Spain (juangavin@gmail.com); Maria Teresa Corradin, Dermatology Unit, Santa Maria degli Angeli Hospital, Pordenone, Italy (teresa.corradin@aas5.sanita.fvg.it); Rosella Gallo, Clinica Dermatologica, IRCCS—AOU San Martino—IST and Department of Health Sciences, University of Genoa, 16 132 Genova, Italy (rs.gallo@unige.it); Magdalena Czarnecka-Operacz, Dermatology Department, University of Medical Sciences, Poznan, Poland (czarnecka.operacz@gmail.com); Mojca Simoncic Godnic, Department of dermatology, Novo mesto, (please edit), Slovenia, Novo Mesto, Slovenia (mojcasg78@gmail.com); Susan M. Cooper, Churchill Hospital, Oxford, UK (sm_nc@btopenworld.com); Cathy M. Green, Department of Dermatology, Ninewells Hospital and Medical School, Dundee, UK (cathy.green@nhs.net); Sharizan Ghaffar, Department of Dermatology, Ninewells Hospital and Medical School, Dundee, UK (NA); Philippa Cousen, James Cook University Hospital, Middlesbrough, UK (philippa.cousen@stees.nhs.uk); Graham A. Johnston, Department of Dermatology, Leicester Royal Infirmary, Leicester, UK (graham.johnston@uhl-tr.nhs.uk); Mahbub M. U. Chowdhury, The Welsh Institute of Dermatology, University Hospital of Wales, Cardiff, UK (mmu.chowdhury@cardiffandvale.wales.nhs.uk); Natalie Stone, Aneurin Bevin Health Board, Newport, Gwent, UK (natalie.stone@wales.nhs.uk); Ian R. White, St. John's Institute of Dermatology, Guy's Hospital, London, UK (ian.white@kcl.ac.uk). Open Access funding enabled and organized by Projekt DEAL. Publisher Copyright: © 2023 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.
PY - 2023/4
Y1 - 2023/4
N2 - Background: Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially occupational allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden for the affected individual and for society. Objectives: To present the sensitization frequencies to the most relevant allergens of the European baseline series in patients with occupational contact dermatitis (OCD) and to compare sensitization profiles of different occupations. Methods: The data of 16 022 patients considered having OCD after patch testing within the European Surveillance System on Contact Allergies (ESSCA) network between January 2011 and December 2020 were evaluated. Patients (n = 46 652) in whom an occupational causation was refuted served as comparison group. Results: The highest percentages of OCD were found among patients working in agriculture, fishery and related workers, metal industry, chemical industry, followed by building and construction industry, health care, food and service industry. Sensitizations to rubber chemicals (thiurams, carbamates, benzothiazoles) and epoxy resins were associated with at least a doubled risk of OCD. After a decline from 2014 onwards, the risks to acquire an occupation-related sensitization to methyl(chloro)isothiazolinone (MCI/MI) and especially to methylisothiazolinone (MI) seem to increase again. Sensitization rates to formaldehyde were stable, and to methyldibromo glutaronitrile (MDBGN) slightly decreasing over time. Conclusions: Among allergens in the European Baseline Series, occupational relevance is most frequently attributed to rubber accelerators, epoxy resins and preservatives.
AB - Background: Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially occupational allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden for the affected individual and for society. Objectives: To present the sensitization frequencies to the most relevant allergens of the European baseline series in patients with occupational contact dermatitis (OCD) and to compare sensitization profiles of different occupations. Methods: The data of 16 022 patients considered having OCD after patch testing within the European Surveillance System on Contact Allergies (ESSCA) network between January 2011 and December 2020 were evaluated. Patients (n = 46 652) in whom an occupational causation was refuted served as comparison group. Results: The highest percentages of OCD were found among patients working in agriculture, fishery and related workers, metal industry, chemical industry, followed by building and construction industry, health care, food and service industry. Sensitizations to rubber chemicals (thiurams, carbamates, benzothiazoles) and epoxy resins were associated with at least a doubled risk of OCD. After a decline from 2014 onwards, the risks to acquire an occupation-related sensitization to methyl(chloro)isothiazolinone (MCI/MI) and especially to methylisothiazolinone (MI) seem to increase again. Sensitization rates to formaldehyde were stable, and to methyldibromo glutaronitrile (MDBGN) slightly decreasing over time. Conclusions: Among allergens in the European Baseline Series, occupational relevance is most frequently attributed to rubber accelerators, epoxy resins and preservatives.
KW - RRID:SCR_001905
KW - baseline series
KW - clinical epidemiology
KW - occupational contact allergy
KW - patch testing
KW - surveillance
UR - http://www.scopus.com/inward/record.url?scp=85147370149&partnerID=8YFLogxK
U2 - https://doi.org/10.1111/cod.14280
DO - https://doi.org/10.1111/cod.14280
M3 - Article
C2 - 36694979
SN - 0105-1873
VL - 88
SP - 263
EP - 274
JO - Contact dermatitis
JF - Contact dermatitis
IS - 4
ER -