Onderzoek naar de tijdelijke behandeling van hoog-normale bloeddruk ter voorkoming van hypertensie en met hypertensie samenhangende orgaanschade: de TIResiAS-studie

B. van den Bogaard; M. Baumann; H. C. P. M. van Weert; H. A. J. Struijker Boudier; G. A. van Montfrans; B. J. H. van den Born

Onderzoek naar de tijdelijke behandeling van hoog-normale bloeddruk ter voorkoming van hypertensie en met hypertensie samenhangende orgaanschade: de TIResiAS-studie

B. van den Bogaard, M. Baumann, H. C. P. M. van Weert, H. A. J. Struijker Boudier, G. A. van Montfrans, B. J. H. van den Born

Research output: Contribution to journal › Article › Professional

2 Citations (Scopus)

Abstract

A recent study from the Framingham cohort showed that persons with high normal blood pressure, also known as prehypertension, are at increased risk for cardiovascular complications and have a 10% annual risk to progress to hypertension. Studies in spontaneous hypertensive rats have demonstrated that it is possible to postpone the development of hypertension and hypertensive organ damage by a temporary anti-hypertensive intervention if started early in life. Recently the TROPHY study showed that treatment with an angiotensin receptor blocker for 2 years was able to delay the progress to hypertension. In a randomized trial in relatively young (age 18-40 years) prehypertensive persons, we aim to investigate whether temporary treatment with an angiotensin-converting enzyme inhibitor, for one year, reduces blood pressure and left ventricular mass two years after cessation of treatment compared to placebo

Original language	Dutch
Pages (from-to)	1800-1802
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	151
Issue number	32
Publication status	Published - 2007

Cite this

@article{fa4886931419429aac60e3570de87242,

title = "Onderzoek naar de tijdelijke behandeling van hoog-normale bloeddruk ter voorkoming van hypertensie en met hypertensie samenhangende orgaanschade: de TIResiAS-studie",

abstract = "A recent study from the Framingham cohort showed that persons with high normal blood pressure, also known as prehypertension, are at increased risk for cardiovascular complications and have a 10% annual risk to progress to hypertension. Studies in spontaneous hypertensive rats have demonstrated that it is possible to postpone the development of hypertension and hypertensive organ damage by a temporary anti-hypertensive intervention if started early in life. Recently the TROPHY study showed that treatment with an angiotensin receptor blocker for 2 years was able to delay the progress to hypertension. In a randomized trial in relatively young (age 18-40 years) prehypertensive persons, we aim to investigate whether temporary treatment with an angiotensin-converting enzyme inhibitor, for one year, reduces blood pressure and left ventricular mass two years after cessation of treatment compared to placebo",

author = "{van den Bogaard}, B. and M. Baumann and {van Weert}, {H. C. P. M.} and {Struijker Boudier}, {H. A. J.} and {van Montfrans}, {G. A.} and {van den Born}, {B. J. H.}",

year = "2007",

language = "Dutch",

volume = "151",

pages = "1800--1802",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "Vereniging Nederlands Tijdschrift voor Geneeskunde",

number = "32",

}

Onderzoek naar de tijdelijke behandeling van hoog-normale bloeddruk ter voorkoming van hypertensie en met hypertensie samenhangende orgaanschade: de TIResiAS-studie. / van den Bogaard, B.; Baumann, M.; van Weert, H. C. P. M. et al.
In: Nederlands Tijdschrift voor Geneeskunde, Vol. 151, No. 32, 2007, p. 1800-1802.

Research output: Contribution to journal › Article › Professional

TY - JOUR

T1 - Onderzoek naar de tijdelijke behandeling van hoog-normale bloeddruk ter voorkoming van hypertensie en met hypertensie samenhangende orgaanschade: de TIResiAS-studie

AU - van den Bogaard, B.

AU - Baumann, M.

AU - van Weert, H. C. P. M.

AU - Struijker Boudier, H. A. J.

AU - van Montfrans, G. A.

AU - van den Born, B. J. H.

PY - 2007

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N2 - A recent study from the Framingham cohort showed that persons with high normal blood pressure, also known as prehypertension, are at increased risk for cardiovascular complications and have a 10% annual risk to progress to hypertension. Studies in spontaneous hypertensive rats have demonstrated that it is possible to postpone the development of hypertension and hypertensive organ damage by a temporary anti-hypertensive intervention if started early in life. Recently the TROPHY study showed that treatment with an angiotensin receptor blocker for 2 years was able to delay the progress to hypertension. In a randomized trial in relatively young (age 18-40 years) prehypertensive persons, we aim to investigate whether temporary treatment with an angiotensin-converting enzyme inhibitor, for one year, reduces blood pressure and left ventricular mass two years after cessation of treatment compared to placebo

AB - A recent study from the Framingham cohort showed that persons with high normal blood pressure, also known as prehypertension, are at increased risk for cardiovascular complications and have a 10% annual risk to progress to hypertension. Studies in spontaneous hypertensive rats have demonstrated that it is possible to postpone the development of hypertension and hypertensive organ damage by a temporary anti-hypertensive intervention if started early in life. Recently the TROPHY study showed that treatment with an angiotensin receptor blocker for 2 years was able to delay the progress to hypertension. In a randomized trial in relatively young (age 18-40 years) prehypertensive persons, we aim to investigate whether temporary treatment with an angiotensin-converting enzyme inhibitor, for one year, reduces blood pressure and left ventricular mass two years after cessation of treatment compared to placebo

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JO - Nederlands Tijdschrift voor Geneeskunde

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