Optimal Vitamin D Status: A Critical Analysis on the Basis of Evidence-Based Medicine

R. Bouillon; N.M. van Schoor; E. Gielen; S. Boonen; C. Mathieu; D. Vanderschueren; P.T.A.M. Lips

doi:https://doi.org/10.1210/jc.2013-1195

Optimal Vitamin D Status: A Critical Analysis on the Basis of Evidence-Based Medicine

R. Bouillon, N.M. van Schoor, E. Gielen, S. Boonen, C. Mathieu, D. Vanderschueren, P.T.A.M. Lips

Research output: Contribution to journal › Article › Academic › peer-review

231 Citations (Scopus)

Abstract

Context: Public health authorities around the world recommend widely variable supplementation strategies for adults, whereas several professional organizations, including The Endocrine Society, recommend higher supplementation. Methods: We analyzed published randomized controlled clinical trials to define the optimal intake or vitamin D status for bone and extra skeletal health. Conclusions: The extra skeletal effects of vitamin D are plausible as based on preclinical data and observational studies. However, a part from the beneficial effectsof800IU/dofvitaminD

Original language	English
Pages (from-to)	E1283-E1304
Journal	Journal of clinical endocrinology and metabolism
Volume	98
Issue number	8
DOIs	https://doi.org/10.1210/jc.2013-1195
Publication status	Published - 2013

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https://doi.org/10.1210/jc.2013-1195

Cite this

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