Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement

Michela Buglione; Roberta Cavagnini; Federico Di Rosario; Marta Maddalo; Lucia Vassalli; Salvatore Grisanti; Stefano Salgarello; Ester Orlandi; Paolo Bossi; Alessandra Majorana; Giorgio Gastaldi; Alfredo Berruti; Fabio Trippa; Pietro Nicolai; Andrei Barasch; Elvio G. Russi; Judith Raber-Durlacher; Barbara Murphy; Stefano M. Magrini

doi:https://doi.org/10.1016/j.critrevonc.2016.03.012

Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement

Michela Buglione, Roberta Cavagnini, Federico Di Rosario, Marta Maddalo, Lucia Vassalli, Salvatore Grisanti, Stefano Salgarello, Ester Orlandi, Paolo Bossi, Alessandra Majorana, Giorgio Gastaldi, Alfredo Berruti, Fabio Trippa, Pietro Nicolai, Andrei Barasch, Elvio G. Russi, Judith Raber-Durlacher, Barbara Murphy, Stefano M. Magrini

Oral and Maxillofacial Surgery (AMC)

Research output: Contribution to journal › Review article › Academic › peer-review

49 Citations (Scopus)

Abstract

Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late toxicities (osteoradionecrosis, xerostomia, trismus, radiation caries etc.) are often debilitating and underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met in Milan with the aim of reaching a consensus on a clinical definition and management of these toxicities. The Delphi Appropriateness method was used for this consensus and external experts evaluated the conclusions. The paper contains 20 clusters of statements about the clinical definition and management of stomatological issues that reached consensus, and offers a review of the literature about these topics. The review was split into two parts: the first part dealt with dental pathologies and osteo-radionecrosis (10 clusters of statements), whereas this second part deals with trismus and xerostomia (10 clusters of statements)

Original language	English
Pages (from-to)	47-54
Journal	Critical Reviews in Oncology/Hematology
Volume	102
DOIs	https://doi.org/10.1016/j.critrevonc.2016.03.012
Publication status	Published - 2016

Access to Document

https://doi.org/10.1016/j.critrevonc.2016.03.012

Cite this

Buglione, M., Cavagnini, R., Di Rosario, F., Maddalo, M., Vassalli, L., Grisanti, S., Salgarello, S., Orlandi, E., Bossi, P., Majorana, A., Gastaldi, G., Berruti, A., Trippa, F., Nicolai, P., Barasch, A., Russi, E. G., Raber-Durlacher, J., Murphy, B., & Magrini, S. M. (2016). Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement. Critical Reviews in Oncology/Hematology, 102, 47-54. https://doi.org/10.1016/j.critrevonc.2016.03.012

@article{2f608946573a42ffb6b2e7b1009505fd,

title = "Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement",

abstract = "Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late toxicities (osteoradionecrosis, xerostomia, trismus, radiation caries etc.) are often debilitating and underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met in Milan with the aim of reaching a consensus on a clinical definition and management of these toxicities. The Delphi Appropriateness method was used for this consensus and external experts evaluated the conclusions. The paper contains 20 clusters of statements about the clinical definition and management of stomatological issues that reached consensus, and offers a review of the literature about these topics. The review was split into two parts: the first part dealt with dental pathologies and osteo-radionecrosis (10 clusters of statements), whereas this second part deals with trismus and xerostomia (10 clusters of statements)",

author = "Michela Buglione and Roberta Cavagnini and {Di Rosario}, Federico and Marta Maddalo and Lucia Vassalli and Salvatore Grisanti and Stefano Salgarello and Ester Orlandi and Paolo Bossi and Alessandra Majorana and Giorgio Gastaldi and Alfredo Berruti and Fabio Trippa and Pietro Nicolai and Andrei Barasch and Russi, {Elvio G.} and Judith Raber-Durlacher and Barbara Murphy and Magrini, {Stefano M.}",

year = "2016",

doi = "https://doi.org/10.1016/j.critrevonc.2016.03.012",

language = "English",

volume = "102",

pages = "47--54",

journal = "Critical Reviews in Oncology/Hematology",

issn = "1040-8428",

publisher = "Elsevier Ireland Ltd",

}

Buglione, M, Cavagnini, R, Di Rosario, F, Maddalo, M, Vassalli, L, Grisanti, S, Salgarello, S, Orlandi, E, Bossi, P, Majorana, A, Gastaldi, G, Berruti, A, Trippa, F, Nicolai, P, Barasch, A, Russi, EG, Raber-Durlacher, J, Murphy, B & Magrini, SM 2016, 'Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement', Critical Reviews in Oncology/Hematology, vol. 102, pp. 47-54. https://doi.org/10.1016/j.critrevonc.2016.03.012

Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement. / Buglione, Michela; Cavagnini, Roberta; Di Rosario, Federico et al.
In: Critical Reviews in Oncology/Hematology, Vol. 102, 2016, p. 47-54.

Research output: Contribution to journal › Review article › Academic › peer-review

TY - JOUR

T1 - Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2). Literature review and consensus statement

AU - Buglione, Michela

AU - Cavagnini, Roberta

AU - Di Rosario, Federico

AU - Maddalo, Marta

AU - Vassalli, Lucia

AU - Grisanti, Salvatore

AU - Salgarello, Stefano

AU - Orlandi, Ester

AU - Bossi, Paolo

AU - Majorana, Alessandra

AU - Gastaldi, Giorgio

AU - Berruti, Alfredo

AU - Trippa, Fabio

AU - Nicolai, Pietro

AU - Barasch, Andrei

AU - Russi, Elvio G.

AU - Raber-Durlacher, Judith

AU - Murphy, Barbara

AU - Magrini, Stefano M.

PY - 2016

Y1 - 2016

N2 - Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late toxicities (osteoradionecrosis, xerostomia, trismus, radiation caries etc.) are often debilitating and underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met in Milan with the aim of reaching a consensus on a clinical definition and management of these toxicities. The Delphi Appropriateness method was used for this consensus and external experts evaluated the conclusions. The paper contains 20 clusters of statements about the clinical definition and management of stomatological issues that reached consensus, and offers a review of the literature about these topics. The review was split into two parts: the first part dealt with dental pathologies and osteo-radionecrosis (10 clusters of statements), whereas this second part deals with trismus and xerostomia (10 clusters of statements)

AB - Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late toxicities (osteoradionecrosis, xerostomia, trismus, radiation caries etc.) are often debilitating and underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met in Milan with the aim of reaching a consensus on a clinical definition and management of these toxicities. The Delphi Appropriateness method was used for this consensus and external experts evaluated the conclusions. The paper contains 20 clusters of statements about the clinical definition and management of stomatological issues that reached consensus, and offers a review of the literature about these topics. The review was split into two parts: the first part dealt with dental pathologies and osteo-radionecrosis (10 clusters of statements), whereas this second part deals with trismus and xerostomia (10 clusters of statements)

U2 - https://doi.org/10.1016/j.critrevonc.2016.03.012

DO - https://doi.org/10.1016/j.critrevonc.2016.03.012

M3 - Review article

C2 - 27061883

SN - 1040-8428

VL - 102

SP - 47

EP - 54

JO - Critical Reviews in Oncology/Hematology

JF - Critical Reviews in Oncology/Hematology

ER -