Orally disintegrating olanzapine and potential differences in treatment-emergent weight gain

Jamie Karagianis; Vicki Poole Hoffmann; Belen Arranz; Tamás Treuer; Gerald A. Maguire; Lieuwe de Haan; Bharat Chawla

doi:https://doi.org/10.1002/hup.933

Orally disintegrating olanzapine and potential differences in treatment-emergent weight gain

Jamie Karagianis, Vicki Poole Hoffmann, Belen Arranz, Tamás Treuer, Gerald A. Maguire, Lieuwe de Haan, Bharat Chawla

Research output: Contribution to journal › Review article › Academic › peer-review

13 Citations (Scopus)

Abstract

Several papers and communications have reported possible weight reduction or less weight gain when patients start or switch to orally disintegrating olanzapine, as contrasted with standard oral olanzapine tablets. In this paper, the current literature is reviewed and hypothesized mechanisms of action are discussed. The data are still preliminary and mechanisms of action are not well understood. Randomized controlled trials are needed to further evaluate change in weight during treatment with orally disintegrating olanzapine

Original language	English
Pages (from-to)	275-281
Journal	Human psychopharmacology
Volume	23
Issue number	4
DOIs	https://doi.org/10.1002/hup.933
Publication status	Published - 2008

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https://doi.org/10.1002/hup.933

Cite this

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title = "Orally disintegrating olanzapine and potential differences in treatment-emergent weight gain",

abstract = "Several papers and communications have reported possible weight reduction or less weight gain when patients start or switch to orally disintegrating olanzapine, as contrasted with standard oral olanzapine tablets. In this paper, the current literature is reviewed and hypothesized mechanisms of action are discussed. The data are still preliminary and mechanisms of action are not well understood. Randomized controlled trials are needed to further evaluate change in weight during treatment with orally disintegrating olanzapine",

author = "Jamie Karagianis and Hoffmann, {Vicki Poole} and Belen Arranz and Tam{\'a}s Treuer and Maguire, {Gerald A.} and {de Haan}, Lieuwe and Bharat Chawla",

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AU - Karagianis, Jamie

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AU - Arranz, Belen

AU - Treuer, Tamás

AU - Maguire, Gerald A.

AU - de Haan, Lieuwe

AU - Chawla, Bharat

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AB - Several papers and communications have reported possible weight reduction or less weight gain when patients start or switch to orally disintegrating olanzapine, as contrasted with standard oral olanzapine tablets. In this paper, the current literature is reviewed and hypothesized mechanisms of action are discussed. The data are still preliminary and mechanisms of action are not well understood. Randomized controlled trials are needed to further evaluate change in weight during treatment with orally disintegrating olanzapine

U2 - https://doi.org/10.1002/hup.933

DO - https://doi.org/10.1002/hup.933

M3 - Review article

C2 - 18338426

SN - 0885-6222

VL - 23

SP - 275

EP - 281

JO - Human psychopharmacology

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