TY - JOUR
T1 - Paediatric patients report lower health-related quality of life in daily clinical practice compared to new normative PedsQLTM data
AU - van Muilekom, Maud M.
AU - Luijten, Michiel A. J.
AU - van Oers, Hedy A.
AU - Conijn, Thirsa
AU - Maurice-Stam, Heleen
AU - the KLIK collaborator group
AU - van Goudoever, Johannes B.
AU - Grootenhuis, Martha A.
AU - Haverman, Lotte
AU - Study group members AMC, null
AU - Menke, Leonie A.
N1 - Funding Information: The data collection in this study was supported by the Dutch National Health Care Institute. TM Publisher Copyright: ©2021 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/7
Y1 - 2021/7
N2 - Aim: To compare Health-Related Quality of Life (HRQOL) of paediatric patients with newly collected HRQOL data of the general Dutch population, explore responses to individual items and investigate variables associated with HRQOL. Methods: Children (8–12y) and adolescents (13–17y) from the general population (N = 966) and from a paediatric population (N = 1209) completed the Pediatric Quality of Life Inventory (PedsQLTM) online via the KLIK Patient-Reported Outcome Measures portal. PedsQLTM scale scores were compared between groups with independent t tests, by age group and gender. Responses to PedsQLTM items were explored using descriptive analyses. Linear regression analyses were performed to determine which variables were associated with HRQOL. Results: Paediatric patients reported worse HRQOL than the general population on all PedsQLTM scales (p ≤.001, d = 0.20–1.03), except social functioning, and a high proportion reported problems on PedsQLTM items, for example, ‘I have trouble sleeping’. Younger age, female gender and school absence were negatively associated with HRQOL (β = −0.37–0.10, p ≤.008). Conclusion: Paediatric patients reported lower HRQOL than the general population, and school absence, female gender and younger age were associated with lower HRQOL. The results underline the importance to structurally monitor paediatric patients’ HRQOL in clinical practice to detect problems and offer the right help on time.
AB - Aim: To compare Health-Related Quality of Life (HRQOL) of paediatric patients with newly collected HRQOL data of the general Dutch population, explore responses to individual items and investigate variables associated with HRQOL. Methods: Children (8–12y) and adolescents (13–17y) from the general population (N = 966) and from a paediatric population (N = 1209) completed the Pediatric Quality of Life Inventory (PedsQLTM) online via the KLIK Patient-Reported Outcome Measures portal. PedsQLTM scale scores were compared between groups with independent t tests, by age group and gender. Responses to PedsQLTM items were explored using descriptive analyses. Linear regression analyses were performed to determine which variables were associated with HRQOL. Results: Paediatric patients reported worse HRQOL than the general population on all PedsQLTM scales (p ≤.001, d = 0.20–1.03), except social functioning, and a high proportion reported problems on PedsQLTM items, for example, ‘I have trouble sleeping’. Younger age, female gender and school absence were negatively associated with HRQOL (β = −0.37–0.10, p ≤.008). Conclusion: Paediatric patients reported lower HRQOL than the general population, and school absence, female gender and younger age were associated with lower HRQOL. The results underline the importance to structurally monitor paediatric patients’ HRQOL in clinical practice to detect problems and offer the right help on time.
KW - Pediatric Quality of Life Inventory
KW - clinical practice
KW - health-related quality of life
KW - paediatric patients
KW - patient-reported outcome measures
UR - http://www.scopus.com/inward/record.url?scp=85105017742&partnerID=8YFLogxK
U2 - https://doi.org/10.1111/apa.15872
DO - https://doi.org/10.1111/apa.15872
M3 - Article
C2 - 33838052
SN - 0803-5253
VL - 110
SP - 2267
EP - 2279
JO - Acta Paediatrica, International Journal of Paediatrics
JF - Acta Paediatrica, International Journal of Paediatrics
IS - 7
ER -