TY - JOUR
T1 - Panethnic Differences in Blood Pressure in Europe: A Systematic Review and Meta-Analysis
AU - Modesti, Pietro Amedeo
AU - Reboldi, Gianpaolo
AU - Cappuccio, Francesco P.
AU - Agyemang, Charles
AU - Remuzzi, Giuseppe
AU - Rapi, Stefano
AU - Perruolo, Eleonora
AU - Parati, Gianfranco
AU - AUTHOR GROUP
AU - Modesti, Pietro A.
AU - Agostoni, Piergiuseppe
AU - Barros, Henrique
AU - Basu, Sanjay
AU - Benetos, Athanase
AU - Ceriello, Antonio
AU - del Prato, Stefano
AU - Kalyesubula, Robert
AU - Kilama, Michael Ochan
AU - O'Brien, Eoin
AU - Perlini, Stefano
AU - Picano, Eugenio
AU - Redon, Josep
AU - Stuckler, David
AU - van Bortel, Luc M.
AU - Zhao, Dong
AU - Bamoshmoosh, Mohamed
AU - Bennet, Louise
AU - Bruno, Rosa Maria
AU - Carlsson, Axel C.
AU - Cifkova, Renata
AU - Fadnes, Lars T.
AU - Grech, Helen
AU - Klocek, Marek
AU - Kumar, Bernadette
AU - Lalic, Nebojsa
AU - Manolis, Athanasios J.
AU - Nørredam, Marie
AU - Massetti, Luciano
AU - de Courten, Maximilian Pangratius
AU - Pereira, Marta
AU - Pratali, Lorenza
AU - Siegert, Andreas
AU - Szklarska, Alicia
AU - Tendera, Michal
AU - Twagirumukiza, Marc
AU - Volodina, Anna
AU - Watfa, Ghassan
AU - Karaye, Kamilu M.
AU - Phanzu, Bernard Kianu
AU - Dzudie, Anastase
AU - N'Guetta, Roland
PY - 2016
Y1 - 2016
N2 - People of Sub Saharan Africa (SSA) and South Asians(SA) ethnic minorities living in Europe have higher risk of stroke than native Europeans(EU). Study objective is to provide an assessment of gender specific absolute differences in office systolic(SBP) and diastolic(DBP) blood pressure(BP) levels between SSA, SA, and EU. We performed a systematic review and meta-analysis of observational studies conducted in Europe that examined BP in non-selected adult SSA, SA and EU subjects. Medline, PubMed, Embase, Web of Science, and Scopus were searched from their inception through January 31st 2015, for relevant articles. Outcome measures were mean SBP and DBP differences between minorities and EU, using a random effects model and tested for heterogeneity. Twenty-one studies involving 9,070 SSA, 18,421 SA, and 130,380 EU were included. Compared with EU, SSA had higher values of both SBP (3.38 mmHg, 95% CI 1.28 to 5.48 mmHg; and 6.00 mmHg, 95% CI 2.22 to 9.78 in men and women respectively) and DBP (3.29 mmHg, 95% CI 1.80 to 4.78; 5.35 mmHg, 95% CI 3.04 to 7.66). SA had lower SBP than EU(-4.57 mmHg, 95% CI -6.20 to -2.93; -2.97 mmHg, 95% CI -5.45 to -0.49) but similar DBP values. Meta-analysis by subgroup showed that SA originating from countries where Islam is the main religion had lower SBP and DBP values than EU. In multivariate meta-regression analyses, SBP difference between minorities and EU populations, was influenced by panethnicity and diabetes prevalence. 1) The higher BP in SSA is maintained over decades, suggesting limited efficacy of prevention strategies in such group in Europe;2) The lower BP in Muslim populations suggests that yet untapped lifestyle and behavioral habits may reveal advantages towards the development of hypertension;3) The additive effect of diabetes, emphasizes the need of new strategies for the control of hypertension in groups at high prevalence of diabetes
AB - People of Sub Saharan Africa (SSA) and South Asians(SA) ethnic minorities living in Europe have higher risk of stroke than native Europeans(EU). Study objective is to provide an assessment of gender specific absolute differences in office systolic(SBP) and diastolic(DBP) blood pressure(BP) levels between SSA, SA, and EU. We performed a systematic review and meta-analysis of observational studies conducted in Europe that examined BP in non-selected adult SSA, SA and EU subjects. Medline, PubMed, Embase, Web of Science, and Scopus were searched from their inception through January 31st 2015, for relevant articles. Outcome measures were mean SBP and DBP differences between minorities and EU, using a random effects model and tested for heterogeneity. Twenty-one studies involving 9,070 SSA, 18,421 SA, and 130,380 EU were included. Compared with EU, SSA had higher values of both SBP (3.38 mmHg, 95% CI 1.28 to 5.48 mmHg; and 6.00 mmHg, 95% CI 2.22 to 9.78 in men and women respectively) and DBP (3.29 mmHg, 95% CI 1.80 to 4.78; 5.35 mmHg, 95% CI 3.04 to 7.66). SA had lower SBP than EU(-4.57 mmHg, 95% CI -6.20 to -2.93; -2.97 mmHg, 95% CI -5.45 to -0.49) but similar DBP values. Meta-analysis by subgroup showed that SA originating from countries where Islam is the main religion had lower SBP and DBP values than EU. In multivariate meta-regression analyses, SBP difference between minorities and EU populations, was influenced by panethnicity and diabetes prevalence. 1) The higher BP in SSA is maintained over decades, suggesting limited efficacy of prevention strategies in such group in Europe;2) The lower BP in Muslim populations suggests that yet untapped lifestyle and behavioral habits may reveal advantages towards the development of hypertension;3) The additive effect of diabetes, emphasizes the need of new strategies for the control of hypertension in groups at high prevalence of diabetes
U2 - https://doi.org/10.1371/journal.pone.0147601
DO - https://doi.org/10.1371/journal.pone.0147601
M3 - Review article
C2 - 26808317
SN - 1932-6203
VL - 11
SP - e0147601
JO - PLOS ONE
JF - PLOS ONE
IS - 1
ER -