TY - JOUR
T1 - Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
AU - Booij, Jan
AU - Adam, Judit A.
AU - van Eerde, Maaike S.
AU - Bronner, Irene M.
N1 - Publisher Copyright: © 2021 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2022/2/1
Y1 - 2022/2/1
N2 - A 47-year-old woman presented with an acute cerebellar syndrome. Neither cerebellar atrophy nor an infarction or tumor was shown on MRI. A diagnostic CT demonstrated enlarged axillary lymph nodes, but no primary tumor. Puncture of these nodes showed non-small cell carcinoma. 18F-FDG PET/CT imaging was performed and suggested an occult breast carcinoma, which was confirmed by pathological examination. It also showed cerebellar hypermetabolism, consistent with a PCS (paraneoplastic cerebellar syndrome). This case shows that 18F-FDG PET imaging may be of value in patients in which a PCS is considered clinically, particularly in patients suspicious for an occult malignancy.
AB - A 47-year-old woman presented with an acute cerebellar syndrome. Neither cerebellar atrophy nor an infarction or tumor was shown on MRI. A diagnostic CT demonstrated enlarged axillary lymph nodes, but no primary tumor. Puncture of these nodes showed non-small cell carcinoma. 18F-FDG PET/CT imaging was performed and suggested an occult breast carcinoma, which was confirmed by pathological examination. It also showed cerebellar hypermetabolism, consistent with a PCS (paraneoplastic cerebellar syndrome). This case shows that 18F-FDG PET imaging may be of value in patients in which a PCS is considered clinically, particularly in patients suspicious for an occult malignancy.
KW - F-FDG PET
KW - cerebellar hypermetabolism
KW - occult breast carcinoma
KW - paraneoplastic cerebellar syndrome
UR - http://www.scopus.com/inward/record.url?scp=85123208255&partnerID=8YFLogxK
U2 - https://doi.org/10.1097/RLU.0000000000004016
DO - https://doi.org/10.1097/RLU.0000000000004016
M3 - Article
C2 - 35006107
SN - 0363-9762
VL - 47
SP - 130
EP - 132
JO - Clinical nuclear medicine
JF - Clinical nuclear medicine
IS - 2
ER -