TY - JOUR
T1 - Parental psychological distress and anxiety after a successful IVF/ICSI procedure with and without preimplantation genetic screening: Follow-up of a randomised controlled trial
AU - Beukers, F.
AU - Houtzager, B. A.
AU - Paap, M. C. S.
AU - Middelburg, K. J.
AU - Hadders-Algra, M.
AU - Bos, A. F.
AU - Kok, J. H.
AU - AUTHOR GROUP
AU - Cobben, Jan Maarten
AU - van der Heide, Maaike
AU - Koomen, Alice
AU - Repping, Sjoerd
AU - Silberbusch, Lobke
AU - Twisk, Moniek
AU - Mastenbroek, Sebastiaan
AU - van der Veen, Fulco
AU - Bos, Arend F.
AU - Haadsma, Maaike
AU - Hadders-Algra, Mijna
AU - Heineman, Maas Jan
AU - van Hoften, Jacorina
AU - Jongbloed-Pereboom, Marjolein
AU - Keating, Paul
AU - Seggers, Jorien
PY - 2012
Y1 - 2012
N2 - Background: Infertility treatment has an acknowledged psychological impact on women and their partners; however, information about the development of parental well-being after child birth is inconclusive. Preimplantation genetic screening (PGS) has been suggested to increase the efficacy of infertility treatments, but the effect it may have on parental well-being is unknown. Aim: To evaluate parental distress and anxiety at one and two years after successful infertility treatment and to explore variables that might affect parental outcome, including PGS and child behaviour. Study design: Follow-up of a randomised controlled trial (RCT) on the efficacy of PGS. Subjects: Parents (n = 101) that successfully underwent IVF/ICSI with or without PGS. Outcome measures: At one and two years, parental distress and anxiety were assessed with the General Health Questionnaire 30 and State Trait Anxiety Inventory, respectively. At two years, child development and behaviour were assessed with the Dutch Bayley Scales of Infant Development-II and the Child Behaviour Checklist 11/2-5, respectively. Results: PGS had no effect on parental distress or anxiety. Child behaviour problems were associated with parental distress and anxiety. There was a main effect of time on parental distress, with distress levels decreasing over time. Conclusions: We found no objection to PGS related to parental psychological distress and anxiety. When parental psychological problems are present after infertility treatment, the results of this study could be useful to support counselling. (c) 2012 Elsevier Ireland Ltd. All rights reserved
AB - Background: Infertility treatment has an acknowledged psychological impact on women and their partners; however, information about the development of parental well-being after child birth is inconclusive. Preimplantation genetic screening (PGS) has been suggested to increase the efficacy of infertility treatments, but the effect it may have on parental well-being is unknown. Aim: To evaluate parental distress and anxiety at one and two years after successful infertility treatment and to explore variables that might affect parental outcome, including PGS and child behaviour. Study design: Follow-up of a randomised controlled trial (RCT) on the efficacy of PGS. Subjects: Parents (n = 101) that successfully underwent IVF/ICSI with or without PGS. Outcome measures: At one and two years, parental distress and anxiety were assessed with the General Health Questionnaire 30 and State Trait Anxiety Inventory, respectively. At two years, child development and behaviour were assessed with the Dutch Bayley Scales of Infant Development-II and the Child Behaviour Checklist 11/2-5, respectively. Results: PGS had no effect on parental distress or anxiety. Child behaviour problems were associated with parental distress and anxiety. There was a main effect of time on parental distress, with distress levels decreasing over time. Conclusions: We found no objection to PGS related to parental psychological distress and anxiety. When parental psychological problems are present after infertility treatment, the results of this study could be useful to support counselling. (c) 2012 Elsevier Ireland Ltd. All rights reserved
U2 - https://doi.org/10.1016/j.earlhumdev.2012.03.001
DO - https://doi.org/10.1016/j.earlhumdev.2012.03.001
M3 - Article
C2 - 22460061
SN - 0378-3782
VL - 88
SP - 725
EP - 730
JO - Early Human Development
JF - Early Human Development
IS - 9
ER -