TY - JOUR
T1 - Parkinson's disease mild cognitive impairment: application and validation of the criteria
T2 - Application and validation of the criteria
AU - Geurtsen, Gert J.
AU - Goldman, Jennifer G.
AU - Schmand, Ben A.
AU - Tröster, Alexander I.
AU - Burn, David J.
AU - Litvan, Irene
AU - AUTHOR GROUP
AU - Filoteo, J. Vincent
AU - Hurtig, Howard
AU - Chen-Plotkin, Alice
AU - Adler, Charles H.
AU - Jacobson, Sandra A.
AU - Leverenz, Jim
AU - Zabetian, Cyrus
AU - Huang, Xuemei
AU - Eslinger, Paul J.
AU - Marras, Connie
AU - Duff-Canning, Sarah
AU - Dalrymple-Alford, John C.
AU - Anderson, Tim J.
AU - Naismith, Sharon L.
AU - Lewis, Simon J. G.
AU - Wu, Ruey-Meei
AU - Yu, Rwei-Ling
AU - Bhattacharyya, Kalyan B.
AU - Williams-Gray, Caroline H.
AU - Breen, David P.
AU - Barker, Roger A.
AU - Yarnall, Alison J.
AU - de Bie, Rob M. A.
AU - Koene, Ted
AU - Klein, Martin
AU - Trautmann, Ellen
AU - Mollenhauer, Brit
AU - Dodel, Richard
AU - Kulisevsky, Jaime
AU - Pagonabaragga, Javier
AU - Rodriguez-Oroz, Maria C.
AU - Gasca-Salas, Carmen
AU - Junque, Carme
AU - Segura, Barbara
AU - Sportiello, Marco Timpano
AU - Cammisuli, Davide M.
AU - Barone, Paolo
AU - Pedersen, Kenn Freddy
AU - Alves, Guido
AU - Hoogland, J.
PY - 2014
Y1 - 2014
N2 - Dementia in Parkinson's disease (PD) is a serious health issue and a major concern for many patients. In most cases mild cognitive impairment (MCI) is considered a transitional stage between normal cognitive functioning and dementia which is of potential importance in the early identification of patients at risk for dementia. Recently, the Movement Disorder Society (MDS) proposed diagnostic criteria for MCI in PD (PD-MCI). These criteria comprise two operationalizations: Level I (based on an abbreviated assessment) and Level II (based on comprehensive neuropsychological evaluation permitting MCI subtyping). These criteria need to be validated. This paper describes a project aiming to validate the MDS PD-MCI criteria by pooling and analyzing cross-sectional and longitudinal neuropsychological databases comprising ≥5,500 PD patients and ≥1,700 controls. After applying the MDS PD-MCI Level I and Level II criteria, rates of conversion to PD-dementia and predictive variables for conversion to PD-dementia will be established. This study will also assist in identifying whether revisions of the PD-MCI criteria are required
AB - Dementia in Parkinson's disease (PD) is a serious health issue and a major concern for many patients. In most cases mild cognitive impairment (MCI) is considered a transitional stage between normal cognitive functioning and dementia which is of potential importance in the early identification of patients at risk for dementia. Recently, the Movement Disorder Society (MDS) proposed diagnostic criteria for MCI in PD (PD-MCI). These criteria comprise two operationalizations: Level I (based on an abbreviated assessment) and Level II (based on comprehensive neuropsychological evaluation permitting MCI subtyping). These criteria need to be validated. This paper describes a project aiming to validate the MDS PD-MCI criteria by pooling and analyzing cross-sectional and longitudinal neuropsychological databases comprising ≥5,500 PD patients and ≥1,700 controls. After applying the MDS PD-MCI Level I and Level II criteria, rates of conversion to PD-dementia and predictive variables for conversion to PD-dementia will be established. This study will also assist in identifying whether revisions of the PD-MCI criteria are required
KW - Parkinson disease
KW - dementia
KW - mild cognitive impairment
KW - neuropsychological tests/standards
KW - validation studies
UR - http://www.scopus.com/inward/record.url?scp=84901855869&partnerID=8YFLogxK
U2 - https://doi.org/10.3233/JPD-130304
DO - https://doi.org/10.3233/JPD-130304
M3 - Article
C2 - 24296865
SN - 1877-7171
VL - 4
SP - 131
EP - 137
JO - Journal of Parkinson s disease
JF - Journal of Parkinson s disease
IS - 2
ER -