Abstract
Observational studies have overwhelmingly shown that variants in the genes CYP2C9 and VKORC1 are significant determinants of individual dose of coumarin anticoagulants needed to maintain a therapeutic international normalized ratio (INR).(1) Until recently, however, few randomized clinical trials had been performed relating to the use of genetic data to predict dosing. Three sucsh clinical trials have now reported their findings
Original language | English |
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Pages (from-to) | 15-17 |
Journal | Clinical Pharmacology and Therapeutics |
Volume | 96 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |