Pearly penile papules: still no reason for uneasiness

Cornelis J A Hogewoning; Maaike C G Bleeker; Adriaan J C van den Brule; Feja J Voorhorst; Rick E van Andel; Elle K Risse; Theo M Starink; Chris J L M Meijer

doi:https://doi.org/10.1067/mjd.2003.420

Pearly penile papules: still no reason for uneasiness

Cornelis J A Hogewoning, Maaike C G Bleeker, Adriaan J C van den Brule, Feja J Voorhorst, Rick E van Andel, Elle K Risse, Theo M Starink, Chris J L M Meijer

Research output: Contribution to journal › Article › Academic › peer-review

20 Citations (Scopus)

Abstract

BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).

OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.

METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.

RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.

CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.

Original language	English
Pages (from-to)	50-4
Number of pages	5
Journal	Journal of the American Academy of Dermatology
Volume	49
Issue number	1
DOIs	https://doi.org/10.1067/mjd.2003.420
Publication status	Published - Jul 2003

Keywords

Adult
Cervical Intraepithelial Neoplasia
Female
Humans
Journal Article
Male
Middle Aged
Papillomaviridae
Penile Diseases
Research Support, Non-U.S. Gov't
Sexual Partners
Uterine Cervical Neoplasms

Access to Document

https://doi.org/10.1067/mjd.2003.420

Cite this

@article{d837137a78d04468a1d49d28dc928d43,

title = "Pearly penile papules: still no reason for uneasiness",

abstract = "BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.",

keywords = "Adult, Cervical Intraepithelial Neoplasia, Female, Humans, Journal Article, Male, Middle Aged, Papillomaviridae, Penile Diseases, Research Support, Non-U.S. Gov't, Sexual Partners, Uterine Cervical Neoplasms",

author = "Hogewoning, {Cornelis J A} and Bleeker, {Maaike C G} and {van den Brule}, {Adriaan J C} and Voorhorst, {Feja J} and {van Andel}, {Rick E} and Risse, {Elle K} and Starink, {Theo M} and Meijer, {Chris J L M}",

year = "2003",

month = jul,

doi = "https://doi.org/10.1067/mjd.2003.420",

language = "English",

volume = "49",

pages = "50--4",

journal = "Journal of the American Academy of Dermatology",

issn = "0190-9622",

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number = "1",

}

TY - JOUR

T1 - Pearly penile papules

T2 - still no reason for uneasiness

AU - Hogewoning, Cornelis J A

AU - Bleeker, Maaike C G

AU - van den Brule, Adriaan J C

AU - Voorhorst, Feja J

AU - van Andel, Rick E

AU - Risse, Elle K

AU - Starink, Theo M

AU - Meijer, Chris J L M

PY - 2003/7

Y1 - 2003/7

N2 - BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.

AB - BACKGROUND: Penile lesions and pearly penile papules (PPP) are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). The former have been associated with human papillomavirus (HPV).OBJECTIVES: We estimated the prevalence of PPP in male sexual partners of women with CIN, and investigated the association between PPP and flat and papular penile lesions found in these men. We further evaluated a possible association between PPP and HPV, age, and CIN grade of the female partner.METHODS: We evaluated by penoscopy the presence of HPV-associated penile lesions and PPP in 226 male sexual partners of women with CIN. HPV was tested by polymerase chain reaction-enzyme immunoassay and in situ hybridization.RESULTS: The prevalence of PPP was 34% and was not associated with the presence of penile lesions or a positive HPV test. Age and CIN grade of the female partner were not related to the presence of PPP.CONCLUSION: The prevalence of PPP in male sexual partners of women with CIN is comparable with the prevalence described in men of more diverse populations. Our data do not support a causative role for HPV in the genesis of PPP.

KW - Adult

KW - Cervical Intraepithelial Neoplasia

KW - Female

KW - Humans

KW - Journal Article

KW - Male

KW - Middle Aged

KW - Papillomaviridae

KW - Penile Diseases

KW - Research Support, Non-U.S. Gov't

KW - Sexual Partners

KW - Uterine Cervical Neoplasms

U2 - https://doi.org/10.1067/mjd.2003.420

DO - https://doi.org/10.1067/mjd.2003.420

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C2 - 12833007

SN - 0190-9622

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