TY - JOUR
T1 - Persistent Deficiency for 40% of Toddlers Who Were Vitamin D Deficient as Neonates, Which Cannot Be Assessed by Examining Symptoms of Rickets
AU - Hogeman, Paul Harold George
AU - Hoevenaar-Blom, Marieke Peternella
AU - Wielders, Jos Peter Marie
PY - 2015/1/1
Y1 - 2015/1/1
N2 - We studied a group of 74 toddlers, mean age 16 months, diagnosed with severe Vitamin D deficiency at birth (cord blood <20 nmol/L 25OH Vitamin D for neonates). Of 74 initially deficient toddlers, 30 did not reach sufficiency at 50 nmol/L level of serum Vitamin D, suggesting persistent Vitamin D deficiency over on average 16 months. Boys remained deficient more often than girls. Even in severely deficient toddlers (25OH Vitamin D <30 nmol/L), no clinical evidence of symptoms of rickets, growth and development retardation, or abnormal serum calcium levels was observed.
AB - We studied a group of 74 toddlers, mean age 16 months, diagnosed with severe Vitamin D deficiency at birth (cord blood <20 nmol/L 25OH Vitamin D for neonates). Of 74 initially deficient toddlers, 30 did not reach sufficiency at 50 nmol/L level of serum Vitamin D, suggesting persistent Vitamin D deficiency over on average 16 months. Boys remained deficient more often than girls. Even in severely deficient toddlers (25OH Vitamin D <30 nmol/L), no clinical evidence of symptoms of rickets, growth and development retardation, or abnormal serum calcium levels was observed.
KW - Vitamin D deficiency
KW - perinatal
KW - rickets
KW - toddlers
UR - http://www.scopus.com/inward/record.url?scp=84983146269&partnerID=8YFLogxK
U2 - https://doi.org/10.1055/s-0035-1554731
DO - https://doi.org/10.1055/s-0035-1554731
M3 - Article
SN - 1879-5390
VL - 5
SP - 12
EP - 14
JO - Journal of Pediatric Biochemistry
JF - Journal of Pediatric Biochemistry
IS - 1
ER -