Perspectives and opportunities for nanomedicine in the management of atherosclerosis

Mark E. Lobatto; Valentin Fuster; Zahi A. Fayad; Willem J. M. Mulder

doi:https://doi.org/10.1038/nrd3578

Perspectives and opportunities for nanomedicine in the management of atherosclerosis

Mark E. Lobatto, Valentin Fuster, Zahi A. Fayad, Willem J. M. Mulder

Research output: Contribution to journal › Review article › Academic › peer-review

336 Citations (Scopus)

Abstract

The use of nanotechnology for medical purposes - nanomedicine - has grown exponentially over the past few decades. This is exemplified by the US Food and Drug Administration's approval of several nanotherapies for various conditions, as well as the funding of nanomedical programmes worldwide. Although originally the domain of anticancer therapy, recent advances have illustrated the considerable potential of nanomedicine in the diagnosis and treatment of atherosclerosis. This Review elaborates on nanoparticle-targeting concepts in atherosclerotic disease, provides an overview of the use of nanomedicine in atherosclerosis, and discusses potential future applications and clinical benefits

Original language	English
Pages (from-to)	835-852
Journal	Nature reviews. Drug discovery
Volume	10
Issue number	11
DOIs	https://doi.org/10.1038/nrd3578
Publication status	Published - 2011

Access to Document

https://doi.org/10.1038/nrd3578

Cite this

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AB - The use of nanotechnology for medical purposes - nanomedicine - has grown exponentially over the past few decades. This is exemplified by the US Food and Drug Administration's approval of several nanotherapies for various conditions, as well as the funding of nanomedical programmes worldwide. Although originally the domain of anticancer therapy, recent advances have illustrated the considerable potential of nanomedicine in the diagnosis and treatment of atherosclerosis. This Review elaborates on nanoparticle-targeting concepts in atherosclerotic disease, provides an overview of the use of nanomedicine in atherosclerosis, and discusses potential future applications and clinical benefits

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