Pessaries in multiple pregnancy as a prevention of preterm birth: the ProTwin Trial (vol 9, 44, 2009)

Sophie M. S. Liem; Dick J. Bekedam; Kitty W. M. Bloemenkamp; Anneke Kwee; Dimitri N. M. Papatsonis; Joris A. M. van der Post; Arianne C. Lim; Hubertina C. J. Scheepers; Christine Willekes; Johannes J. Duvekot; Marc Spaanderman; Martina Porath; Jim van Eyck; Monique C. Haak; Marielle G. van Pampus; Hein W. Bruinse; Ben Willem J. Mol; Maud A. Hegeman

doi:https://doi.org/10.1186/1471-2393-12-37

Pessaries in multiple pregnancy as a prevention of preterm birth: the ProTwin Trial (vol 9, 44, 2009)

Sophie M. S. Liem, Dick J. Bekedam, Kitty W. M. Bloemenkamp, Anneke Kwee, Dimitri N. M. Papatsonis, Joris A. M. van der Post, Arianne C. Lim, Hubertina C. J. Scheepers, Christine Willekes, Johannes J. Duvekot, Marc Spaanderman, Martina Porath, Jim van Eyck, Monique C. Haak, Marielle G. van Pampus, Hein W. Bruinse, Ben Willem J. Mol, Maud A. Hegeman

Research output: Contribution to journal › Comment/Letter to the editor › Academic

1 Citation (Scopus)

Abstract

ABSTRACT: The initial sample size calculation in our protocol (Hegeman et al, BMC Pregnancy Childbirth, 2009, 9:44) was based on the expected proportion of 'bad neonatal outcome' in the intervention group (3.9%) and control group (7.2%) and accounts for the fact that the outcomes in children form multiple pregnancies are non-independent using an intra class correlation of 0.6. As the intervention is performed on the mother, analysis should be done on the maternal level. This adjustment was made during recruitment and approved by the medical ethics committee of the Academic Medical Centre in Amsterdam (ref. No. MEC 09/107). The sample size is calculated based on the primary outcome 'bad neonatal outcome'

Original language	English
Pages (from-to)	37
Journal	BMC pregnancy and childbirth
Volume	12
Issue number	1
DOIs	https://doi.org/10.1186/1471-2393-12-37
Publication status	Published - 2012

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https://doi.org/10.1186/1471-2393-12-37

Cite this

Liem, S. M. S., Bekedam, D. J., Bloemenkamp, K. W. M., Kwee, A., Papatsonis, D. N. M., van der Post, J. A. M., Lim, A. C., Scheepers, H. C. J., Willekes, C., Duvekot, J. J., Spaanderman, M., Porath, M., van Eyck, J., Haak, M. C., van Pampus, M. G., Bruinse, H. W., Mol, B. W. J., & Hegeman, M. A. (2012). Pessaries in multiple pregnancy as a prevention of preterm birth: the ProTwin Trial (vol 9, 44, 2009). BMC pregnancy and childbirth, 12(1), 37. https://doi.org/10.1186/1471-2393-12-37

@article{63ba7c3fd50c4364b4acde89e2b25a6a,

title = "Pessaries in multiple pregnancy as a prevention of preterm birth: the ProTwin Trial (vol 9, 44, 2009)",

abstract = "ABSTRACT: The initial sample size calculation in our protocol (Hegeman et al, BMC Pregnancy Childbirth, 2009, 9:44) was based on the expected proportion of 'bad neonatal outcome' in the intervention group (3.9%) and control group (7.2%) and accounts for the fact that the outcomes in children form multiple pregnancies are non-independent using an intra class correlation of 0.6. As the intervention is performed on the mother, analysis should be done on the maternal level. This adjustment was made during recruitment and approved by the medical ethics committee of the Academic Medical Centre in Amsterdam (ref. No. MEC 09/107). The sample size is calculated based on the primary outcome 'bad neonatal outcome'",

author = "Liem, {Sophie M. S.} and Bekedam, {Dick J.} and Bloemenkamp, {Kitty W. M.} and Anneke Kwee and Papatsonis, {Dimitri N. M.} and {van der Post}, {Joris A. M.} and Lim, {Arianne C.} and Scheepers, {Hubertina C. J.} and Christine Willekes and Duvekot, {Johannes J.} and Marc Spaanderman and Martina Porath and {van Eyck}, Jim and Haak, {Monique C.} and {van Pampus}, {Marielle G.} and Bruinse, {Hein W.} and Mol, {Ben Willem J.} and Hegeman, {Maud A.}",

year = "2012",

doi = "https://doi.org/10.1186/1471-2393-12-37",

language = "English",

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publisher = "BioMed Central",

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Liem, SMS, Bekedam, DJ, Bloemenkamp, KWM, Kwee, A, Papatsonis, DNM, van der Post, JAM, Lim, AC, Scheepers, HCJ, Willekes, C, Duvekot, JJ, Spaanderman, M, Porath, M, van Eyck, J, Haak, MC, van Pampus, MG, Bruinse, HW, Mol, BWJ & Hegeman, MA 2012, 'Pessaries in multiple pregnancy as a prevention of preterm birth: the ProTwin Trial (vol 9, 44, 2009)', BMC pregnancy and childbirth, vol. 12, no. 1, pp. 37. https://doi.org/10.1186/1471-2393-12-37

TY - JOUR

T1 - Pessaries in multiple pregnancy as a prevention of preterm birth: the ProTwin Trial (vol 9, 44, 2009)

AU - Liem, Sophie M. S.

AU - Bekedam, Dick J.

AU - Bloemenkamp, Kitty W. M.

AU - Kwee, Anneke

AU - Papatsonis, Dimitri N. M.

AU - van der Post, Joris A. M.

AU - Lim, Arianne C.

AU - Scheepers, Hubertina C. J.

AU - Willekes, Christine

AU - Duvekot, Johannes J.

AU - Spaanderman, Marc

AU - Porath, Martina

AU - van Eyck, Jim

AU - Haak, Monique C.

AU - van Pampus, Marielle G.

AU - Bruinse, Hein W.

AU - Mol, Ben Willem J.

AU - Hegeman, Maud A.

PY - 2012

Y1 - 2012

N2 - ABSTRACT: The initial sample size calculation in our protocol (Hegeman et al, BMC Pregnancy Childbirth, 2009, 9:44) was based on the expected proportion of 'bad neonatal outcome' in the intervention group (3.9%) and control group (7.2%) and accounts for the fact that the outcomes in children form multiple pregnancies are non-independent using an intra class correlation of 0.6. As the intervention is performed on the mother, analysis should be done on the maternal level. This adjustment was made during recruitment and approved by the medical ethics committee of the Academic Medical Centre in Amsterdam (ref. No. MEC 09/107). The sample size is calculated based on the primary outcome 'bad neonatal outcome'

AB - ABSTRACT: The initial sample size calculation in our protocol (Hegeman et al, BMC Pregnancy Childbirth, 2009, 9:44) was based on the expected proportion of 'bad neonatal outcome' in the intervention group (3.9%) and control group (7.2%) and accounts for the fact that the outcomes in children form multiple pregnancies are non-independent using an intra class correlation of 0.6. As the intervention is performed on the mother, analysis should be done on the maternal level. This adjustment was made during recruitment and approved by the medical ethics committee of the Academic Medical Centre in Amsterdam (ref. No. MEC 09/107). The sample size is calculated based on the primary outcome 'bad neonatal outcome'

U2 - https://doi.org/10.1186/1471-2393-12-37

DO - https://doi.org/10.1186/1471-2393-12-37

M3 - Comment/Letter to the editor

C2 - 22621699

SN - 1471-2393

VL - 12

SP - 37

JO - BMC pregnancy and childbirth

JF - BMC pregnancy and childbirth

IS - 1

ER -