TY - JOUR
T1 - Pharmacological and Nonpharmacological Studies on Coronavirus Disease 2019
T2 - A Mini-review of the Recent Evidence
AU - Bahmani, Amir Hossein Alizadeh
AU - Hoorang, Mehdi
AU - Hosseini, Sheida
AU - Eskandari, Mehrnoosh
AU - Shayestehfard, Kiana
AU - Shekoohi, Mahyar
AU - Hatami-Mazinani, Nazafarin
AU - Afifi, Saba
AU - Sabzghabaee, Ali Mohammad
AU - Peymani, Payam
N1 - Copyright: © 2021 Journal of Research in Pharmacy Practice.
PY - 2021/4/30
Y1 - 2021/4/30
N2 - Coronavirus 19 (COVID-19) is an extremely transmittable microbial infection that has emerged in Wuhan (China) in late 2019, leading to severe acute respiratory syndrome coronavirus 2 syndrome, and caused a pandemic all over the globe. This study is a systematic review of all 927 clinical trial studies performed worldwide from the beginning of the COVID-19 mysterious pandemic in China. These researches have registered in different databases. According to the best of our knowledge, China (74.82%), the United States (4.49%), and France (2.72%) have the most significant number of clinical trials, respectively. Clinical trials can be randomized or nonrandomized. Due to our results, 32.58% of studies were randomized, and 7.12% were not randomized. Most of the studies were open-labeled studies (22.44%), and double-blinded (4.42%) and quadruple blinded (2.48%) studies stand in second and third place regarding the number of trials, respectively. The direction and quantity of clinical trials attempted to identify a possible cure for COVID-19 demonstrates the depth of this crisis. As we are writing this article, a significant international endeavor will find a cure or vaccine for containing this devastating and mysterious disease.
AB - Coronavirus 19 (COVID-19) is an extremely transmittable microbial infection that has emerged in Wuhan (China) in late 2019, leading to severe acute respiratory syndrome coronavirus 2 syndrome, and caused a pandemic all over the globe. This study is a systematic review of all 927 clinical trial studies performed worldwide from the beginning of the COVID-19 mysterious pandemic in China. These researches have registered in different databases. According to the best of our knowledge, China (74.82%), the United States (4.49%), and France (2.72%) have the most significant number of clinical trials, respectively. Clinical trials can be randomized or nonrandomized. Due to our results, 32.58% of studies were randomized, and 7.12% were not randomized. Most of the studies were open-labeled studies (22.44%), and double-blinded (4.42%) and quadruple blinded (2.48%) studies stand in second and third place regarding the number of trials, respectively. The direction and quantity of clinical trials attempted to identify a possible cure for COVID-19 demonstrates the depth of this crisis. As we are writing this article, a significant international endeavor will find a cure or vaccine for containing this devastating and mysterious disease.
U2 - https://doi.org/10.4103/jrpp.JRPP_20_71
DO - https://doi.org/10.4103/jrpp.JRPP_20_71
M3 - Review article
C2 - 33912499
SN - 2319-9644
VL - 9
SP - 175
EP - 180
JO - Journal of research in pharmacy practice
JF - Journal of research in pharmacy practice
IS - 4
ER -