Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy

C.R. Garrett; L.L. Siu; A. El-Khoueiry; J. Buter; C.M. Rocha-Lima; J. Marshall; P. LoRusso; P. Major; J. Chemidlin; O. Mokliatchouk; L. Velasquez; W. Hayes; D. Feltquate; S. Syed; S. Ford; G. Kollia; S. Galbraith; D.S.A. Nuyten

doi:https://doi.org/10.1038/bjc.2011.182

Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy

C.R. Garrett, L.L. Siu, A. El-Khoueiry, J. Buter, C.M. Rocha-Lima, J. Marshall, P. LoRusso, P. Major, J. Chemidlin, O. Mokliatchouk, L. Velasquez, W. Hayes, D. Feltquate, S. Syed, S. Ford, G. Kollia, S. Galbraith, D.S.A. Nuyten

Medical oncology (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

30 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	44-52
Journal	British journal of cancer
Volume	105
Issue number	1
DOIs	https://doi.org/10.1038/bjc.2011.182
Publication status	Published - 2011

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https://doi.org/10.1038/bjc.2011.182

https://research.vumc.nl/ws/files/874364/282670.pdf

Cite this

Garrett, C. R., Siu, L. L., El-Khoueiry, A., Buter, J., Rocha-Lima, C. M., Marshall, J., LoRusso, P., Major, P., Chemidlin, J., Mokliatchouk, O., Velasquez, L., Hayes, W., Feltquate, D., Syed, S., Ford, S., Kollia, G., Galbraith, S., & Nuyten, D. S. A. (2011). Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy. British journal of cancer, 105(1), 44-52. https://doi.org/10.1038/bjc.2011.182

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author = "C.R. Garrett and L.L. Siu and A. El-Khoueiry and J. Buter and C.M. Rocha-Lima and J. Marshall and P. LoRusso and P. Major and J. Chemidlin and O. Mokliatchouk and L. Velasquez and W. Hayes and D. Feltquate and S. Syed and S. Ford and G. Kollia and S. Galbraith and D.S.A. Nuyten",

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Garrett, CR, Siu, LL, El-Khoueiry, A, Buter, J, Rocha-Lima, CM, Marshall, J, LoRusso, P, Major, P, Chemidlin, J, Mokliatchouk, O, Velasquez, L, Hayes, W, Feltquate, D, Syed, S, Ford, S, Kollia, G, Galbraith, S & Nuyten, DSA 2011, 'Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy', British journal of cancer, vol. 105, no. 1, pp. 44-52. https://doi.org/10.1038/bjc.2011.182

Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy. / Garrett, C.R.; Siu, L.L.; El-Khoueiry, A. et al.
In: British journal of cancer, Vol. 105, No. 1, 2011, p. 44-52.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy

AU - Garrett, C.R.

AU - Siu, L.L.

AU - El-Khoueiry, A.

AU - Buter, J.

AU - Rocha-Lima, C.M.

AU - Marshall, J.

AU - LoRusso, P.

AU - Major, P.

AU - Chemidlin, J.

AU - Mokliatchouk, O.

AU - Velasquez, L.

AU - Hayes, W.

AU - Feltquate, D.

AU - Syed, S.

AU - Ford, S.

AU - Kollia, G.

AU - Galbraith, S.

AU - Nuyten, D.S.A.

PY - 2011

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DO - https://doi.org/10.1038/bjc.2011.182

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JF - British journal of cancer

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Garrett CR, Siu LL, El-Khoueiry A, Buter J, Rocha-Lima CM, Marshall J et al. Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy. British journal of cancer. 2011;105(1):44-52. doi: https://doi.org/10.1038/bjc.2011.182