TY - JOUR
T1 - Physical activity and its correlates in people with cystic fibrosis
T2 - a systematic review
AU - Kinaupenne, Manon
AU - de Craemer, Marieke
AU - Schaballie, Heidi
AU - Vandekerckhove, Kristof
AU - van Biervliet, Stephanie
AU - Demeyer, Heleen
N1 - Funding Information: Support statement: H. Demeyer and M. De Craemer are senior post-doctoral researchers of Fonds Wetenschappelijk Onderzoek. Funding information for this article has been deposited with the Crossref Funder Registry. Publisher Copyright: © The authors 2022.
PY - 2022/9/30
Y1 - 2022/9/30
N2 - Cystic fibrosis (CF) is a life-shortening genetic disease, affecting multiple life domains including physical activity (PA). Although higher PA levels are associated with multiple health benefits, little insight exists on the PA level of people with CF (PwCF) compared to healthy peers. Evidence on the influencing factors (i.e. correlates) of PA in this clinical population is scarce, but essential to fully understand their PA behaviour. Therefore, the present review aims to provide an overview of the PA level of PwCF compared to healthy peers, and the correlates of PA in PwCF. A systematic search of three databases resulted in 46 included studies. Analysis of 16 studies showed that the CF population is equally active compared to healthy peers, but there is a trend towards less high-intensity PA in youths with CF. Furthermore, PA is positively associated with quality of life, lung function, (maximal) exercise capacity, bone mineral density and quadriceps force. Also, PA was lower on weekdays compared to weekend days and lower when experiencing pulmonary exacerbations. More high-quality research is required in PwCF, particularly longitudinal studies that further explore the correlates of PA, with PA investigated as a primary outcome and measured objectively.
AB - Cystic fibrosis (CF) is a life-shortening genetic disease, affecting multiple life domains including physical activity (PA). Although higher PA levels are associated with multiple health benefits, little insight exists on the PA level of people with CF (PwCF) compared to healthy peers. Evidence on the influencing factors (i.e. correlates) of PA in this clinical population is scarce, but essential to fully understand their PA behaviour. Therefore, the present review aims to provide an overview of the PA level of PwCF compared to healthy peers, and the correlates of PA in PwCF. A systematic search of three databases resulted in 46 included studies. Analysis of 16 studies showed that the CF population is equally active compared to healthy peers, but there is a trend towards less high-intensity PA in youths with CF. Furthermore, PA is positively associated with quality of life, lung function, (maximal) exercise capacity, bone mineral density and quadriceps force. Also, PA was lower on weekdays compared to weekend days and lower when experiencing pulmonary exacerbations. More high-quality research is required in PwCF, particularly longitudinal studies that further explore the correlates of PA, with PA investigated as a primary outcome and measured objectively.
UR - http://www.scopus.com/inward/record.url?scp=85138935487&partnerID=8YFLogxK
U2 - https://doi.org/10.1183/16000617.0010-2022
DO - https://doi.org/10.1183/16000617.0010-2022
M3 - Article
SN - 0905-9180
VL - 31
JO - European Respiratory Review
JF - European Respiratory Review
IS - 165
M1 - 220010
ER -