Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration

Osvaldo P. Almeida; Annemiek Dols; Machteld A.J.T. Blanken; Soham Rej; Hilary P. Blumberg; Luca Villa; Brent P. Forester; Orestes V. Forlenza; Ariel Gildengers; Eduard Vieta; Esther Jimenez; Benoit Mulsant; Sigfried Schouws; Shangying Tsai; Nicole C.M. Korten; Ashley Sutherland; Farren B.S. Briggs; Leon Flicker; Lisa T. Eyler; Martha Sajatovic

doi:https://doi.org/10.1016/j.jagp.2021.12.006

Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration

Osvaldo P. Almeida, Annemiek Dols, Machteld A.J.T. Blanken, Soham Rej, Hilary P. Blumberg, Luca Villa, Brent P. Forester, Orestes V. Forlenza, Ariel Gildengers, Eduard Vieta, Esther Jimenez, Benoit Mulsant, Sigfried Schouws, Shangying Tsai, Nicole C.M. Korten, Ashley Sutherland, Farren B.S. Briggs, Leon Flicker, Lisa T. Eyler, Martha Sajatovic

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

Objectives: To compare the prevalence of physical morbidities among men and women with older adult bipolar disorder (OABD), and men with and without OABD. Methods: Cross-sectional analysis of the collaborative Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) database and non-OABD data from the Health in Men Study. OABD defined as bipolar disorder among adults aged greater than or equal to 50 years. Outcomes of interest were diseases affecting the cardiovascular, respiratory, gastrointestinal, renal, musculoskeletal and endocrinological systems. Results: We examined 1407 participants with OABD aged 50–95 years, of whom 787 were women. More women than men showed evidence of morbidities affecting the respiratory, gastrointestinal, musculoskeletal and endocrinological systems. More men with than without OABD showed evidence of cardiovascular, renal and endocrinological diseases. Conclusion: GAGE-BD data showed that physical morbidities affect more women than men with OABD, and more men with than without OABD. The underlying reasons for these differences require clarification.

Original language	English
Pages (from-to)	727-732
Number of pages	6
Journal	American Journal of Geriatric Psychiatry
Volume	30
Issue number	6
Early online date	11 Dec 2021
DOIs	https://doi.org/10.1016/j.jagp.2021.12.006
Publication status	Published - Jun 2022

Keywords

Bipolar disorder
Medical morbidity
Men
Old age
Physical illness
Sex
Women

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https://doi.org/10.1016/j.jagp.2021.12.006

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Almeida, O. P., Dols, A., Blanken, M. A. J. T., Rej, S., Blumberg, H. P., Villa, L., Forester, B. P., Forlenza, O. V., Gildengers, A., Vieta, E., Jimenez, E., Mulsant, B., Schouws, S., Tsai, S., Korten, N. C. M., Sutherland, A., Briggs, F. B. S., Flicker, L., Eyler, L. T., & Sajatovic, M. (2022). Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration. American Journal of Geriatric Psychiatry, 30(6), 727-732. https://doi.org/10.1016/j.jagp.2021.12.006

@article{59453e973d254e6e80d2b3b0d77ef233,

title = "Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration",

abstract = "Objectives: To compare the prevalence of physical morbidities among men and women with older adult bipolar disorder (OABD), and men with and without OABD. Methods: Cross-sectional analysis of the collaborative Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) database and non-OABD data from the Health in Men Study. OABD defined as bipolar disorder among adults aged greater than or equal to 50 years. Outcomes of interest were diseases affecting the cardiovascular, respiratory, gastrointestinal, renal, musculoskeletal and endocrinological systems. Results: We examined 1407 participants with OABD aged 50–95 years, of whom 787 were women. More women than men showed evidence of morbidities affecting the respiratory, gastrointestinal, musculoskeletal and endocrinological systems. More men with than without OABD showed evidence of cardiovascular, renal and endocrinological diseases. Conclusion: GAGE-BD data showed that physical morbidities affect more women than men with OABD, and more men with than without OABD. The underlying reasons for these differences require clarification.",

keywords = "Bipolar disorder, Medical morbidity, Men, Old age, Physical illness, Sex, Women",

author = "Almeida, {Osvaldo P.} and Annemiek Dols and Blanken, {Machteld A.J.T.} and Soham Rej and Blumberg, {Hilary P.} and Luca Villa and Forester, {Brent P.} and Forlenza, {Orestes V.} and Ariel Gildengers and Eduard Vieta and Esther Jimenez and Benoit Mulsant and Sigfried Schouws and Shangying Tsai and Korten, {Nicole C.M.} and Ashley Sutherland and Briggs, {Farren B.S.} and Leon Flicker and Eyler, {Lisa T.} and Martha Sajatovic",

note = "Funding Information: This project was supported by the International Society for Bipolar Disorders (ISBD) Bowden Massey Strategic Research Initiative. This publication's contents are solely the responsibility of the authors and do not necessarily represent the official views of ISBD. The ISBD is a 401c3 non-profit organization whose mission is to foster international collaboration in education and research. For more information, visit www.isbd.org and www.gage-bd.org . Publisher Copyright: {\textcopyright} 2021 American Association for Geriatric Psychiatry",

year = "2022",

month = jun,

doi = "https://doi.org/10.1016/j.jagp.2021.12.006",

language = "English",

volume = "30",

pages = "727--732",

journal = "American Journal of Geriatric Psychiatry",

issn = "1064-7481",

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Almeida, OP, Dols, A , Blanken, MAJT, Rej, S, Blumberg, HP, Villa, L, Forester, BP, Forlenza, OV, Gildengers, A, Vieta, E, Jimenez, E, Mulsant, B, Schouws, S, Tsai, S, Korten, NCM, Sutherland, A, Briggs, FBS, Flicker, L, Eyler, LT & Sajatovic, M 2022, 'Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration', American Journal of Geriatric Psychiatry, vol. 30, no. 6, pp. 727-732. https://doi.org/10.1016/j.jagp.2021.12.006

TY - JOUR

T1 - Physical Health Burden Among Older Men and Women With Bipolar Disorder

T2 - Results From the Gage-Bd Collaboration

AU - Almeida, Osvaldo P.

AU - Dols, Annemiek

AU - Blanken, Machteld A.J.T.

AU - Rej, Soham

AU - Blumberg, Hilary P.

AU - Villa, Luca

AU - Forester, Brent P.

AU - Forlenza, Orestes V.

AU - Gildengers, Ariel

AU - Vieta, Eduard

AU - Jimenez, Esther

AU - Mulsant, Benoit

AU - Schouws, Sigfried

AU - Tsai, Shangying

AU - Korten, Nicole C.M.

AU - Sutherland, Ashley

AU - Briggs, Farren B.S.

AU - Flicker, Leon

AU - Eyler, Lisa T.

AU - Sajatovic, Martha

N1 - Funding Information: This project was supported by the International Society for Bipolar Disorders (ISBD) Bowden Massey Strategic Research Initiative. This publication's contents are solely the responsibility of the authors and do not necessarily represent the official views of ISBD. The ISBD is a 401c3 non-profit organization whose mission is to foster international collaboration in education and research. For more information, visit www.isbd.org and www.gage-bd.org . Publisher Copyright: © 2021 American Association for Geriatric Psychiatry

PY - 2022/6

Y1 - 2022/6

N2 - Objectives: To compare the prevalence of physical morbidities among men and women with older adult bipolar disorder (OABD), and men with and without OABD. Methods: Cross-sectional analysis of the collaborative Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) database and non-OABD data from the Health in Men Study. OABD defined as bipolar disorder among adults aged greater than or equal to 50 years. Outcomes of interest were diseases affecting the cardiovascular, respiratory, gastrointestinal, renal, musculoskeletal and endocrinological systems. Results: We examined 1407 participants with OABD aged 50–95 years, of whom 787 were women. More women than men showed evidence of morbidities affecting the respiratory, gastrointestinal, musculoskeletal and endocrinological systems. More men with than without OABD showed evidence of cardiovascular, renal and endocrinological diseases. Conclusion: GAGE-BD data showed that physical morbidities affect more women than men with OABD, and more men with than without OABD. The underlying reasons for these differences require clarification.

AB - Objectives: To compare the prevalence of physical morbidities among men and women with older adult bipolar disorder (OABD), and men with and without OABD. Methods: Cross-sectional analysis of the collaborative Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) database and non-OABD data from the Health in Men Study. OABD defined as bipolar disorder among adults aged greater than or equal to 50 years. Outcomes of interest were diseases affecting the cardiovascular, respiratory, gastrointestinal, renal, musculoskeletal and endocrinological systems. Results: We examined 1407 participants with OABD aged 50–95 years, of whom 787 were women. More women than men showed evidence of morbidities affecting the respiratory, gastrointestinal, musculoskeletal and endocrinological systems. More men with than without OABD showed evidence of cardiovascular, renal and endocrinological diseases. Conclusion: GAGE-BD data showed that physical morbidities affect more women than men with OABD, and more men with than without OABD. The underlying reasons for these differences require clarification.

KW - Bipolar disorder

KW - Medical morbidity

KW - Men

KW - Old age

KW - Physical illness

KW - Sex

KW - Women

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U2 - https://doi.org/10.1016/j.jagp.2021.12.006

DO - https://doi.org/10.1016/j.jagp.2021.12.006

M3 - Article

C2 - 34980553

SN - 1064-7481

VL - 30

SP - 727

EP - 732

JO - American Journal of Geriatric Psychiatry

JF - American Journal of Geriatric Psychiatry

IS - 6

ER -

Physical Health Burden Among Older Men and Women With Bipolar Disorder: Results From the Gage-Bd Collaboration

Abstract

Keywords

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