TY - JOUR
T1 - Physical impairment and perceived general health preceding critical illness is predictive of survival
AU - Hofhuis, José G. M.
AU - Abu-Hanna, Ameen
AU - de Zwart, Lisa
AU - Hovingh, Aly
AU - Spronk, Peter E.
PY - 2019
Y1 - 2019
N2 - Purpose: We hypothesized that item response based assessment of physical reserve preceding ICU admission is a predictor of survival. Methods: We evaluated physical functioning using the Academic Medical Center Linear Disability Score (ALDS) and quality of life using the first question (SF-1) and the physical component score (PCS-12) from the Short-form 12 (SF-12) before admission by patients or by close proxies within 72 h after ICU admission during 1 year. Results: We developed four logistic regression models to predict 1 year mortality using the predictors age, gender, ALDS, SF-1, PCS-12. A total of 510 patients participated. Twelve months after ICU discharge, 110 patients (22%) had died. Pre-admission ALDS (p =.004), and SF-1 (p =.012) improved the prediction models with age and gender PCS-12 showed no association with mortality (p =.062). Adding the ALDS (p =.049) and the SF-1 (p =.048) to a model with age, gender and the APACHE II score (improved the model. Adding PCS-12 showed no association with mortality (p =.355). Conclusions: Physical reserve as assessed by ALDS and perceived general health, preceding ICU admission is predictive of mortality. Obtaining patient's physical reserve or pre-existing perceived general health should be part of routine assessment whether a patient may benefit from ICU admission.
AB - Purpose: We hypothesized that item response based assessment of physical reserve preceding ICU admission is a predictor of survival. Methods: We evaluated physical functioning using the Academic Medical Center Linear Disability Score (ALDS) and quality of life using the first question (SF-1) and the physical component score (PCS-12) from the Short-form 12 (SF-12) before admission by patients or by close proxies within 72 h after ICU admission during 1 year. Results: We developed four logistic regression models to predict 1 year mortality using the predictors age, gender, ALDS, SF-1, PCS-12. A total of 510 patients participated. Twelve months after ICU discharge, 110 patients (22%) had died. Pre-admission ALDS (p =.004), and SF-1 (p =.012) improved the prediction models with age and gender PCS-12 showed no association with mortality (p =.062). Adding the ALDS (p =.049) and the SF-1 (p =.048) to a model with age, gender and the APACHE II score (improved the model. Adding PCS-12 showed no association with mortality (p =.355). Conclusions: Physical reserve as assessed by ALDS and perceived general health, preceding ICU admission is predictive of mortality. Obtaining patient's physical reserve or pre-existing perceived general health should be part of routine assessment whether a patient may benefit from ICU admission.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85061077706&origin=inward
U2 - https://doi.org/10.1016/j.jcrc.2019.01.027
DO - https://doi.org/10.1016/j.jcrc.2019.01.027
M3 - Article
C2 - 30745286
SN - 0883-9441
VL - 51
SP - 51
EP - 56
JO - Journal of Critical Care
JF - Journal of Critical Care
ER -