TY - JOUR
T1 - Postnatal acute famine and risk of overweight: the dutch hungerwinter study
AU - van Abeelen, Annet F. M.
AU - Elias, Sjoerd G.
AU - Roseboom, Tessa J.
AU - Bossuyt, Patrick M. M.
AU - van der Schouw, Yvonne T.
AU - Grobbee, Diederick E.
AU - Uiterwaal, Cuno S. P. M.
PY - 2012
Y1 - 2012
N2 - Objective. To examine the association between undernutrition during postnatal periods of development and the risk of overweight in adulthood. Methods. We studied 8,091 women from Prospect-EPIC, exposed to the Dutch famine at ages between 0 and 21 years, recruited at ages between 49 and 70 years. We used linear and logistic regression models to explore the effect of famine on BMI, waist circumference, and the risk of overweight. Results. Overall, postnatal famine exposure was associated with increased BMI and waist circumference in a dose-dependent manner (P for trend < 0.01). Furthermore, risk of overweight was increased following famine exposure (P for trend = 0.01), with those severely exposed at ages 0-9 years having 25% (95% CI 1.05 to 1.50) higher risk compared to unexposed women. Conclusions. This study is the first to directly show a positive association between short and transient undernutrition during postnatal development and BMI, waist circumference, and overweight in adulthood
AB - Objective. To examine the association between undernutrition during postnatal periods of development and the risk of overweight in adulthood. Methods. We studied 8,091 women from Prospect-EPIC, exposed to the Dutch famine at ages between 0 and 21 years, recruited at ages between 49 and 70 years. We used linear and logistic regression models to explore the effect of famine on BMI, waist circumference, and the risk of overweight. Results. Overall, postnatal famine exposure was associated with increased BMI and waist circumference in a dose-dependent manner (P for trend < 0.01). Furthermore, risk of overweight was increased following famine exposure (P for trend = 0.01), with those severely exposed at ages 0-9 years having 25% (95% CI 1.05 to 1.50) higher risk compared to unexposed women. Conclusions. This study is the first to directly show a positive association between short and transient undernutrition during postnatal development and BMI, waist circumference, and overweight in adulthood
U2 - https://doi.org/10.1155/2012/936509
DO - https://doi.org/10.1155/2012/936509
M3 - Article
C2 - 22611413
SN - 1687-9759
VL - 2012
SP - 936509
JO - International journal of pediatrics
JF - International journal of pediatrics
ER -