TY - JOUR
T1 - Practical Approach for Angina and Non-Obstructive Coronary Arteries
T2 - A State-of-the-Art Review
AU - Boerhout, Coen K. M.
AU - Beijk, Marcel A. M.
AU - Damman, Peter
AU - Piek, Jan J.
AU - van de Hoef, Tim P.
N1 - Funding Information: The authors received no financial support for the research, authorship, and/or publication of this article. Publisher Copyright: © 2023. The Korean Society of Cardiology.
PY - 2023
Y1 - 2023
N2 - Anginal symptoms are frequently encountered in patients without the presence of significant obstructive coronary artery disease (CAD). It is increasingly recognized that vasomotor disorders, such as an abnormal vasodilatory capacity of the coronary microcirculation or coronary vasospasm, are the dominant pathophysiological substrate in these patients. Although the evidence with respect to angina in patients with non-obstructive coronary arteries is accumulating, the diagnosis and treatment of these patients remains challenging. In this review, we aimed to provide a comprehensive overview regarding the pathophysiological origins of angina with non-obstructive coronary arteries disorders and its diagnostic and therapeutic considerations. Hereby, we provide a practical approach for the management of patents with angina and non-obstructive CAD.
AB - Anginal symptoms are frequently encountered in patients without the presence of significant obstructive coronary artery disease (CAD). It is increasingly recognized that vasomotor disorders, such as an abnormal vasodilatory capacity of the coronary microcirculation or coronary vasospasm, are the dominant pathophysiological substrate in these patients. Although the evidence with respect to angina in patients with non-obstructive coronary arteries is accumulating, the diagnosis and treatment of these patients remains challenging. In this review, we aimed to provide a comprehensive overview regarding the pathophysiological origins of angina with non-obstructive coronary arteries disorders and its diagnostic and therapeutic considerations. Hereby, we provide a practical approach for the management of patents with angina and non-obstructive CAD.
KW - ANOCA
KW - Abnormal vasodilatory capacity
KW - Coronary microvascular disease
KW - Vasospasm
UR - http://www.scopus.com/inward/record.url?scp=85166640588&partnerID=8YFLogxK
U2 - https://doi.org/10.4070/kcj.2023.0109
DO - https://doi.org/10.4070/kcj.2023.0109
M3 - Article
C2 - 37525496
SN - 1738-5520
VL - 53
JO - Korean Circulation Journal
JF - Korean Circulation Journal
M1 - e52
ER -