TY - JOUR
T1 - Prenatal screening for orofacial clefts in the Netherlands: A preliminary report on the impact of a national screening system
AU - Mink van der Molen, Aebele B.
AU - Maarse, Wies
AU - Pistorius, Lou
AU - de Veye, Henriette Swanenburg
AU - Breugem, Corstiaan C.
PY - 2011
Y1 - 2011
N2 - In the Netherlands a new and countrywide routine screening system for physical congenital anomalies was introduced by legislation in 2007. The screening was aimed initially at Down syndrome, but under specific conditions secondary screening for cleft lip and palate and other congenital malformations is performed as well. This article gives an overview of the Dutch system, with a focus on cleft lip (and palate) and the report of one center's experience. In general, voluntary termination of pregnancy in the second trimester has increased slightly since the introduction of the current system, but the termination-of-pregnancy rate for isolated cleft lip and palate remains limited in the Netherlands.
AB - In the Netherlands a new and countrywide routine screening system for physical congenital anomalies was introduced by legislation in 2007. The screening was aimed initially at Down syndrome, but under specific conditions secondary screening for cleft lip and palate and other congenital malformations is performed as well. This article gives an overview of the Dutch system, with a focus on cleft lip (and palate) and the report of one center's experience. In general, voluntary termination of pregnancy in the second trimester has increased slightly since the introduction of the current system, but the termination-of-pregnancy rate for isolated cleft lip and palate remains limited in the Netherlands.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79952569155&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/21142688
U2 - https://doi.org/10.1597/09-021
DO - https://doi.org/10.1597/09-021
M3 - Review article
C2 - 21142688
SN - 1055-6656
VL - 48
SP - 183
EP - 189
JO - Cleft palate-craniofacial journal
JF - Cleft palate-craniofacial journal
IS - 2
ER -