Prognosis of constipation: clinical factors and colonic transit time: clinical factors and colonic transit time

F. de Lorijn, M.P. van Wijk, J.B. Reitsma, R. van Ginkel, J.A.J.M. Taminiau, M.A. Benninga

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Background: Measurement of colonic transit time (CTT) is sometimes used in the evaluation of patients with chronic constipation. Aim: To investigate the relation between symptoms and CTT, and to assess the importance of symptoms and CTT in predicting outcome. Methods: Between 1995 and 2000, 169 consecutive patients (median age 8.4 years, 65% boys) fulfilling the criteria for constipation were enrolled. During the intervention and follow up period, all kept a diary to record symptoms. CTT was measured at entry to the study. Results: At entry, defecation frequency was lower in girls than in boys, while the frequency of encopresis episodes was higher in boys. CTT values were significantly higher in those with a low defecation frequency (less than or equal to 1/week) and a high frequency of encopresis (greater than or equal to 2/day). However, 50% had CTT values within the normal range. Successful outcome occurred more often in those with a rectal impaction. CTT results,100 hours were not predictive of outcome. However, those with CTT > 100 hours were less likely to have had a successful outcome. Conclusion: The presence of a rectal impaction at presentation is associated with a better outcome at one year. A CTT > 100 hours is associated with a poor outcome at one year
Original languageUndefined/Unknown
Pages (from-to)723-727
Number of pages5
JournalArchives of disease in childhood
Issue number8
Publication statusPublished - Aug 2004


  • AMC wi-eigen
  • Child
  • Chronic Disease
  • Colon/physiopathology
  • Constipation/physiopathology
  • Defecation/physiology
  • Encopresis/physiopathology
  • Fecal Impaction/physiopathology
  • Female
  • Gastrointestinal Transit/physiology
  • Humans
  • Male
  • Prognosis
  • Rectum/physiopathology
  • Severity of Illness Index
  • Sex Factors

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