Prognostic factors in adult soft tissue sarcomas of the head and neck: A single-centre experience: A single-centre experience

R. de Bree; P. van der Valk; D.J. Kuik; P.J. van Diest; P. Doornaert; J. Buter; S.E.J. Eerenstein; J.A. Langedijk; I. van der Waal; C.R. Leemans; Johannes A. Langendijk

doi:https://doi.org/10.1016/j.oraloncology.2005.11.009

Prognostic factors in adult soft tissue sarcomas of the head and neck: A single-centre experience: A single-centre experience

R. de Bree, P. van der Valk, D.J. Kuik, P.J. van Diest, P. Doornaert, J. Buter, S.E.J. Eerenstein, J.A. Langedijk, I. van der Waal, C.R. Leemans, Johannes A. Langendijk

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Adult soft tissue sarcomas of the head and neck are rare and consist of a variety of histopathological subtypes and sites. The purpose of this study was to review patients treated for adult soft tissue sarcomas of the head and neck at our institute. The medical records of 41 adult patients treated for head and neck soft tissue sarcomas between 1983 and 2004 were reviewed. Thirty-six tumours were histologically reviewed. Histopathological revision showed that 7% of the original sarcomas were found not to be sarcomas and 39% of the sarcoma subtypes changed. Multivariate analysis showed that surgical margin status and lymph node metastases are the most important prognostic factors. Review of histopathological examination of tumours showed a change in subtype in a substantial number of head and neck sarcomas. Negative surgical margins are an important prognostic factor, but are difficult to obtain in head and neck sarcomas.

Original language	English
Pages (from-to)	703-709
Number of pages	7
Journal	Oral Oncology
Volume	42
Issue number	7
DOIs	https://doi.org/10.1016/j.oraloncology.2005.11.009
Publication status	Published - Aug 2006

Keywords

Head and neck
Histopathology
Prognostic factors
Soft tissue sarcoma

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de Bree, R., van der Valk, P., Kuik, D. J., van Diest, P. J., Doornaert, P., Buter, J., Eerenstein, S. E. J., Langedijk, J. A., van der Waal, I., Leemans, C. R., & Langendijk, J. A. (2006). Prognostic factors in adult soft tissue sarcomas of the head and neck: A single-centre experience: A single-centre experience. Oral Oncology, 42(7), 703-709. https://doi.org/10.1016/j.oraloncology.2005.11.009

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title = "Prognostic factors in adult soft tissue sarcomas of the head and neck: A single-centre experience: A single-centre experience",

abstract = "Adult soft tissue sarcomas of the head and neck are rare and consist of a variety of histopathological subtypes and sites. The purpose of this study was to review patients treated for adult soft tissue sarcomas of the head and neck at our institute. The medical records of 41 adult patients treated for head and neck soft tissue sarcomas between 1983 and 2004 were reviewed. Thirty-six tumours were histologically reviewed. Histopathological revision showed that 7% of the original sarcomas were found not to be sarcomas and 39% of the sarcoma subtypes changed. Multivariate analysis showed that surgical margin status and lymph node metastases are the most important prognostic factors. Review of histopathological examination of tumours showed a change in subtype in a substantial number of head and neck sarcomas. Negative surgical margins are an important prognostic factor, but are difficult to obtain in head and neck sarcomas.",

keywords = "Head and neck, Histopathology, Prognostic factors, Soft tissue sarcoma",

author = "{de Bree}, R. and {van der Valk}, P. and D.J. Kuik and {van Diest}, P.J. and P. Doornaert and J. Buter and S.E.J. Eerenstein and J.A. Langedijk and {van der Waal}, I. and C.R. Leemans and Langendijk, {Johannes A.}",

year = "2006",

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language = "English",

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de Bree, R, van der Valk, P, Kuik, DJ, van Diest, PJ, Doornaert, P , Buter, J , Eerenstein, SEJ, Langedijk, JA, van der Waal, I , Leemans, CR & Langendijk, JA 2006, 'Prognostic factors in adult soft tissue sarcomas of the head and neck: A single-centre experience: A single-centre experience', Oral Oncology, vol. 42, no. 7, pp. 703-709. https://doi.org/10.1016/j.oraloncology.2005.11.009

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AU - van Diest, P.J.

AU - Doornaert, P.

AU - Buter, J.

AU - Eerenstein, S.E.J.

AU - Langedijk, J.A.

AU - van der Waal, I.

AU - Leemans, C.R.

AU - Langendijk, Johannes A.

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AB - Adult soft tissue sarcomas of the head and neck are rare and consist of a variety of histopathological subtypes and sites. The purpose of this study was to review patients treated for adult soft tissue sarcomas of the head and neck at our institute. The medical records of 41 adult patients treated for head and neck soft tissue sarcomas between 1983 and 2004 were reviewed. Thirty-six tumours were histologically reviewed. Histopathological revision showed that 7% of the original sarcomas were found not to be sarcomas and 39% of the sarcoma subtypes changed. Multivariate analysis showed that surgical margin status and lymph node metastases are the most important prognostic factors. Review of histopathological examination of tumours showed a change in subtype in a substantial number of head and neck sarcomas. Negative surgical margins are an important prognostic factor, but are difficult to obtain in head and neck sarcomas.

KW - Head and neck

KW - Histopathology

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Prognostic factors in adult soft tissue sarcomas of the head and neck: A single-centre experience: A single-centre experience

Abstract

Keywords

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