TY - JOUR
T1 - Prognostication after cardiac arrest
AU - Horn, Janneke
AU - Cronberg, Tobias
AU - Taccone, Fabio S.
PY - 2014
Y1 - 2014
N2 - The prognosis of patients with postanoxic coma (PAC) after cardiac arrest is a challenging task for clinicians. The need for early and accurate prognostic predictors is crucial. Treatment with therapeutic hypothermia and sedation alters the reliability of neurological examination. Considering the extensive literature existing on this topic, we aimed to provide a practical approach on how to predict outcome in patients with PAC, particularly in those treated with therapeutic hypothermia. Recovery of motor responses can take several days and can therefore not be used to assess the extent of brain injury in the early phase after cardiac arrest. Additional tools, including electroencephalography, somatosensory-evoked potentials, biomarkers and radiological imaging, may help to determine the prognosis. Nevertheless, treatment with therapeutic hypothermia, including prolonged sedation, has changed the predictive value of these tools. For reliable prediction of outcome in patients with PAC, various prognostic methods should be combined with the standard neurological examination in a multimodal approach
AB - The prognosis of patients with postanoxic coma (PAC) after cardiac arrest is a challenging task for clinicians. The need for early and accurate prognostic predictors is crucial. Treatment with therapeutic hypothermia and sedation alters the reliability of neurological examination. Considering the extensive literature existing on this topic, we aimed to provide a practical approach on how to predict outcome in patients with PAC, particularly in those treated with therapeutic hypothermia. Recovery of motor responses can take several days and can therefore not be used to assess the extent of brain injury in the early phase after cardiac arrest. Additional tools, including electroencephalography, somatosensory-evoked potentials, biomarkers and radiological imaging, may help to determine the prognosis. Nevertheless, treatment with therapeutic hypothermia, including prolonged sedation, has changed the predictive value of these tools. For reliable prediction of outcome in patients with PAC, various prognostic methods should be combined with the standard neurological examination in a multimodal approach
U2 - https://doi.org/10.1097/MCC.0000000000000093
DO - https://doi.org/10.1097/MCC.0000000000000093
M3 - Review article
C2 - 24717695
SN - 1070-5295
VL - 20
SP - 280
EP - 286
JO - Current Opinion in Critical Care
JF - Current Opinion in Critical Care
IS - 3
ER -