TY - JOUR
T1 - Progress update from the hippocampal subfields group
AU - Olsen, Rosanna K.
AU - Carr, Valerie A.
AU - Daugherty, Ana M.
AU - la Joie, Renaud
AU - Amaral, Robert S. C.
AU - Amunts, Katrin
AU - Augustinack, Jean C.
AU - Bakker, Arnold
AU - Bender, Andrew R.
AU - Berron, David
AU - Boccardi, Marina
AU - Bocchetta, Martina
AU - Burggren, Alison C.
AU - Chakravarty, M. Mallar
AU - Chételat, Gaël
AU - de Flores, Robin
AU - DeKraker, Jordan
AU - Ding, Song-Lin
AU - Geerlings, Mirjam I.
AU - Huang, Yushan
AU - Insausti, Ricardo
AU - Johnson, Elliott G.
AU - Kanel, Prabesh
AU - Kedo, Olga
AU - Kennedy, Kristen M.
AU - Keresztes, Attila
AU - Lee, Joshua K.
AU - Lindenberger, Ulman
AU - Mueller, Susanne G.
AU - Mulligan, Elizabeth M.
AU - Ofen, Noa
AU - Palombo, Daniela J.
AU - Pasquini, Lorenzo
AU - Pluta, John
AU - Raz, Naftali
AU - Rodrigue, Karen M.
AU - Schlichting, Margaret L.
AU - Lee Shing, Yee
AU - Stark, Craig E. L.
AU - Steve, Trevor A.
AU - Suthana, Nanthia A.
AU - Wang, Lei
AU - Werkle-Bergner, Markus
AU - Yushkevich, Paul A.
AU - Yu, Qijing
AU - Hippocampal Subfields Group
AU - Wisse, Laura E. M.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Introduction: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence. Methods: Our international working group, funded by the EU Joint Programme–Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption. Results: This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures. Discussion: A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.
AB - Introduction: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on in vivo magnetic resonance imaging hinders the ability to integrate findings across studies. We aim to develop a harmonized protocol based on expert consensus and histological evidence. Methods: Our international working group, funded by the EU Joint Programme–Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol for segmentation of medial temporal lobe regions. The working group uses a novel postmortem data set and online consensus procedures to ensure validity and facilitate adoption. Results: This progress report describes the initial results and milestones that we have achieved to date, including the development of a draft protocol and results from the initial reliability tests and consensus procedures. Discussion: A harmonized protocol will enable the standardization of segmentation methods across laboratories interested in medial temporal lobe research worldwide.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066990984&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/31245529
U2 - https://doi.org/10.1016/j.dadm.2019.04.001
DO - https://doi.org/10.1016/j.dadm.2019.04.001
M3 - Article
C2 - 31245529
SN - 2352-8729
VL - 11
SP - 439
EP - 449
JO - Alzheimer's & dementia : diagnosis, assessment & disease monitoring
JF - Alzheimer's & dementia : diagnosis, assessment & disease monitoring
ER -