Psychoradiological Biomarkers for Psychopharmaceutical Effects

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Abstract

The application of personalized medicine to psychiatry is challenging. Psychoradiology could provide biomarkers based on objective tests in support of the diagnostic classifications and treatment planning. We review potential psychoradiological biomarkers for psychopharmaceutical effects. Although none of the biomarkers reviewed are yet of sufficient clinical utility to inform the selection of a specific pharmacologic compound for an individual patient, there is strong consensus that advanced multimodal approaches will contribute to discovery of novel treatment predictors in psychiatric disorders. Progress has been sufficient to warrant enthusiasm, in which application of neuroimaging-based biomarkers would represent a paradigm shift and modernization of psychiatric practice.
Original languageEnglish
Pages (from-to)53-63
Number of pages11
JournalNeuroimaging Clinics of North America
Volume30
Issue number1
DOIs
Publication statusPublished - Feb 2020

Keywords

  • Antidepressants
  • Predictive imaging biomarkers
  • Psychoradiology
  • Stimulants
  • Treatment response

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