TY - JOUR
T1 - QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies
AU - Whiting, Penny F.
AU - Rutjes, Anne W. S.
AU - Westwood, Marie E.
AU - Mallett, Susan
AU - Deeks, Jonathan J.
AU - Reitsma, Johannes B.
AU - Leeflang, Mariska M. G.
AU - Sterne, Jonathan A. C.
AU - Bossuyt, Patrick M. M.
AU - AUTHOR GROUP
AU - Altman, Doug
AU - Begg, Colin
AU - Beynon, Rebecca
AU - Lijmer, Jeroen
AU - Cornell, John
AU - Davenport, Clare
AU - Khan, Khalid
AU - Glasziou, Paul
AU - Horvath, Rita
AU - Irwig, Les
AU - Macaskill, Petra
AU - Hyde, Chris
AU - Moons, Karel G. M.
AU - Raatz, Heike
AU - Shaw, Beth
AU - Tan, Toni
AU - van der Windt, Danielle
AU - Virgili, Gianni
PY - 2011
Y1 - 2011
N2 - In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies
AB - In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies
U2 - https://doi.org/10.1059/0003-4819-155-8-201110180-00009
DO - https://doi.org/10.1059/0003-4819-155-8-201110180-00009
M3 - Article
C2 - 22007046
SN - 0003-4819
VL - 155
SP - 529
EP - 536
JO - Annals of Internal Medicine
JF - Annals of Internal Medicine
IS - 8
ER -