TY - JOUR
T1 - Quality of life after brachytherapy in patients with glioblastoma multiforme
AU - Koot, R. W.
AU - de Heer, K.
AU - Oort, F. J.
AU - Hulshof, M. C. C. M.
AU - Bosch, D. A.
AU - de Haes, J. C. J. M.
PY - 2004
Y1 - 2004
N2 - As quality of life (QoL) is perhaps the most important outcome for patients treated for glioblastoma multiforme (GBM), we measured QoL in GBM patients after brachytherapy. QoL was assessed by questionnaires for both patients and partners before brachytherapy and at various times during follow-up in 21 GBM patients by an extension of the Rotterdam Symptom Checklist (e-RSCL), consisting of four subscales. The Karnofsky Performance Scale (KPS) was also measured. Analysis of variance was done to evaluate the direct effect of brachytherapy (visit 1-2, short-term) and during follow up (visit 1-4, longer-term). Significant short-term effects were found for two subscales of the e-RSCL. Longer-term effects were found for all four subscales and for the KPS. A high correlation between partner and patient's QoL assessment was found. QoL in GBM patients after brachytherapy can therefore be carefully monitored with a subjective instrument such as the e-RSCL. Patients and partners experience QoL equally. (C) 2004 Elsevier Ltd. All rights reserved
AB - As quality of life (QoL) is perhaps the most important outcome for patients treated for glioblastoma multiforme (GBM), we measured QoL in GBM patients after brachytherapy. QoL was assessed by questionnaires for both patients and partners before brachytherapy and at various times during follow-up in 21 GBM patients by an extension of the Rotterdam Symptom Checklist (e-RSCL), consisting of four subscales. The Karnofsky Performance Scale (KPS) was also measured. Analysis of variance was done to evaluate the direct effect of brachytherapy (visit 1-2, short-term) and during follow up (visit 1-4, longer-term). Significant short-term effects were found for two subscales of the e-RSCL. Longer-term effects were found for all four subscales and for the KPS. A high correlation between partner and patient's QoL assessment was found. QoL in GBM patients after brachytherapy can therefore be carefully monitored with a subjective instrument such as the e-RSCL. Patients and partners experience QoL equally. (C) 2004 Elsevier Ltd. All rights reserved
U2 - https://doi.org/10.1016/j.ejca.2004.01.018
DO - https://doi.org/10.1016/j.ejca.2004.01.018
M3 - Article
C2 - 15093576
SN - 0959-8049
VL - 40
SP - 1013
EP - 1020
JO - European journal of cancer (Oxford, England
JF - European journal of cancer (Oxford, England
IS - 7
ER -