RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury

Mark C. Dessing; Wilco P. Pulskens; Gwendoline J. Teske; Loes M. Butter; Tom van der Poll; Huan Yang; Kevin J. Tracey; Peter P. Nawroth; Angelika Bierhaus; Sandrine Florquin; Jaklien C. Leemans

doi:https://doi.org/10.1159/000334251

RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury

Mark C. Dessing, Wilco P. Pulskens, Gwendoline J. Teske, Loes M. Butter, Tom van der Poll, Huan Yang, Kevin J. Tracey, Peter P. Nawroth, Angelika Bierhaus, Sandrine Florquin, Jaklien C. Leemans

Research output: Contribution to journal › Article › Academic › peer-review

19 Citations (Scopus)

Abstract

The receptor for advanced glycation end products (RAGE) mediates a variety of inflammatory responses in renal diseases, but its role in renal ischemia/reperfusion (I/R) injury is unknown. We showed that during renal I/R, RAGE ligands HMGB1 and S100B are expressed. However, RAGE deficiency does not affect renal injury and function upon I/R-induced injury. Copyright (C) 2011 S. Karger AG, Basel

Original language	English
Pages (from-to)	80-85
Journal	Journal of innate immunity
Volume	4
Issue number	1
DOIs	https://doi.org/10.1159/000334251
Publication status	Published - 2012

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https://doi.org/10.1159/000334251

Cite this

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title = "RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury",

abstract = "The receptor for advanced glycation end products (RAGE) mediates a variety of inflammatory responses in renal diseases, but its role in renal ischemia/reperfusion (I/R) injury is unknown. We showed that during renal I/R, RAGE ligands HMGB1 and S100B are expressed. However, RAGE deficiency does not affect renal injury and function upon I/R-induced injury. Copyright (C) 2011 S. Karger AG, Basel",

author = "Dessing, {Mark C.} and Pulskens, {Wilco P.} and Teske, {Gwendoline J.} and Butter, {Loes M.} and {van der Poll}, Tom and Huan Yang and Tracey, {Kevin J.} and Nawroth, {Peter P.} and Angelika Bierhaus and Sandrine Florquin and Leemans, {Jaklien C.}",

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doi = "https://doi.org/10.1159/000334251",

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AU - Dessing, Mark C.

AU - Pulskens, Wilco P.

AU - Teske, Gwendoline J.

AU - Butter, Loes M.

AU - van der Poll, Tom

AU - Yang, Huan

AU - Tracey, Kevin J.

AU - Nawroth, Peter P.

AU - Bierhaus, Angelika

AU - Florquin, Sandrine

AU - Leemans, Jaklien C.

PY - 2012

Y1 - 2012

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AB - The receptor for advanced glycation end products (RAGE) mediates a variety of inflammatory responses in renal diseases, but its role in renal ischemia/reperfusion (I/R) injury is unknown. We showed that during renal I/R, RAGE ligands HMGB1 and S100B are expressed. However, RAGE deficiency does not affect renal injury and function upon I/R-induced injury. Copyright (C) 2011 S. Karger AG, Basel

U2 - https://doi.org/10.1159/000334251

DO - https://doi.org/10.1159/000334251

M3 - Article

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