Rationale and Technique for Percutaneous Coronary Intervention of Chronic Total Occlusions

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Abstract

Chronic total occlusions (CTOs) represent the “last frontier” of percutaneous coronary interventions (PCI). CTOs are frequently (~30 %) detected on diagnostic coronary angiograms, but CTO PCI is currently performed infrequently mainly because of higher technical difficulty and perceived risk of complications. Nonetheless, successful CTO PCI can significantly improve the patient’s quality of life, improve left ventricular function, reduce the need for subsequent coronary artery bypass graft surgery, and possibly improve long-term survival. The introduction of novel catheters, guidewires, adjunctive imaging, PCI techniques, and higher operator volumes has led to an increased success rate of CTO PCI. Moreover, the introduction of drug-eluting stents has led to higher rates of sustained patency following CTO recanalization. This chapter aims to provide an overview of the anatomy and histopathology of CTOs, a concise review of techniques and devices for CTO PCI, and a comprehensive summary of the evidence regarding the clinical relevance and rationale of CTO PCI.

Original languageEnglish
Title of host publicationPanVascular Medicine, Second Edition
PublisherSpringer Berlin Heidelberg
Pages2281-2296
Number of pages16
ISBN (Electronic)9783642370786
ISBN (Print)9783642370779
DOIs
Publication statusPublished - 1 Jan 2015

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