Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia

B. F. Jacobson; E. Schapkaitz; M. Mer; S. Louw; S. Haas; H. R. Buller; B. Brenner; A. T. O. Abdool-Carrim; P. de Jong; P. Hsu; D. Jankelow; M. Lebos; B. Levy; H. Radford; P. Rowji; L. Redman; M. Sussman; D. van der Jagt; P. F. Wessels; P. G. Williams

doi:https://doi.org/10.7196/SAMJ.2021.v111i6.15772

Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia

B. F. Jacobson, E. Schapkaitz, M. Mer, S. Louw, S. Haas, H. R. Buller, B. Brenner, A. T. O. Abdool-Carrim, P. de Jong, P. Hsu, D. Jankelow, M. Lebos, B. Levy, H. Radford, P. Rowji, L. Redman, M. Sussman, D. van der Jagt, P. F. Wessels, P. G. Williams

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

Abstract

There have recently been safety concerns regarding an increased risk of vaccine-induced immune thrombotic thrombocytopenia (VITT) following administration of SARS-CoV-2 adenoviral vector vaccines. The Southern African Society of Thrombosis and Haemostasis reviewed the emerging literature on this idiosyncratic complication. A draft document was produced and revised by consensus agreement by a panel of professionals from various specialties. The recommendations were adjudicated by independent international experts to avoid local bias. We present concise, practical guidelines for the clinical management of VITT.

Original language	English
Pages (from-to)	535-537
Number of pages	3
Journal	South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
Volume	111
Issue number	6
DOIs	https://doi.org/10.7196/SAMJ.2021.v111i6.15772
Publication status	Published - 2021

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Jacobson, B. F., Schapkaitz, E., Mer, M., Louw, S., Haas, S., Buller, H. R., Brenner, B., Abdool-Carrim, A. T. O., de Jong, P., Hsu, P., Jankelow, D., Lebos, M., Levy, B., Radford, H., Rowji, P., Redman, L., Sussman, M., van der Jagt, D., Wessels, P. F., & Williams, P. G. (2021). Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 111(6), 535-537. https://doi.org/10.7196/SAMJ.2021.v111i6.15772

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title = "Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia",

abstract = "There have recently been safety concerns regarding an increased risk of vaccine-induced immune thrombotic thrombocytopenia (VITT) following administration of SARS-CoV-2 adenoviral vector vaccines. The Southern African Society of Thrombosis and Haemostasis reviewed the emerging literature on this idiosyncratic complication. A draft document was produced and revised by consensus agreement by a panel of professionals from various specialties. The recommendations were adjudicated by independent international experts to avoid local bias. We present concise, practical guidelines for the clinical management of VITT.",

author = "Jacobson, {B. F.} and E. Schapkaitz and M. Mer and S. Louw and S. Haas and Buller, {H. R.} and B. Brenner and Abdool-Carrim, {A. T. O.} and {de Jong}, P. and P. Hsu and D. Jankelow and M. Lebos and B. Levy and H. Radford and P. Rowji and L. Redman and M. Sussman and {van der Jagt}, D. and Wessels, {P. F.} and Williams, {P. G.}",

year = "2021",

doi = "https://doi.org/10.7196/SAMJ.2021.v111i6.15772",

language = "English",

volume = "111",

pages = "535--537",

journal = "South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde",

issn = "0256-9574",

publisher = "Health and Medical Publishing Group",

number = "6",

}

Jacobson, BF, Schapkaitz, E, Mer, M, Louw, S, Haas, S, Buller, HR, Brenner, B, Abdool-Carrim, ATO, de Jong, P, Hsu, P, Jankelow, D, Lebos, M, Levy, B, Radford, H, Rowji, P, Redman, L, Sussman, M, van der Jagt, D, Wessels, PF & Williams, PG 2021, 'Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia', South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, vol. 111, no. 6, pp. 535-537. https://doi.org/10.7196/SAMJ.2021.v111i6.15772

TY - JOUR

T1 - Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia

AU - Jacobson, B. F.

AU - Schapkaitz, E.

AU - Mer, M.

AU - Louw, S.

AU - Haas, S.

AU - Buller, H. R.

AU - Brenner, B.

AU - Abdool-Carrim, A. T. O.

AU - de Jong, P.

AU - Hsu, P.

AU - Jankelow, D.

AU - Lebos, M.

AU - Levy, B.

AU - Radford, H.

AU - Rowji, P.

AU - Redman, L.

AU - Sussman, M.

AU - van der Jagt, D.

AU - Wessels, P. F.

AU - Williams, P. G.

PY - 2021

Y1 - 2021

N2 - There have recently been safety concerns regarding an increased risk of vaccine-induced immune thrombotic thrombocytopenia (VITT) following administration of SARS-CoV-2 adenoviral vector vaccines. The Southern African Society of Thrombosis and Haemostasis reviewed the emerging literature on this idiosyncratic complication. A draft document was produced and revised by consensus agreement by a panel of professionals from various specialties. The recommendations were adjudicated by independent international experts to avoid local bias. We present concise, practical guidelines for the clinical management of VITT.

AB - There have recently been safety concerns regarding an increased risk of vaccine-induced immune thrombotic thrombocytopenia (VITT) following administration of SARS-CoV-2 adenoviral vector vaccines. The Southern African Society of Thrombosis and Haemostasis reviewed the emerging literature on this idiosyncratic complication. A draft document was produced and revised by consensus agreement by a panel of professionals from various specialties. The recommendations were adjudicated by independent international experts to avoid local bias. We present concise, practical guidelines for the clinical management of VITT.

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U2 - https://doi.org/10.7196/SAMJ.2021.v111i6.15772

DO - https://doi.org/10.7196/SAMJ.2021.v111i6.15772

M3 - Article

SN - 0256-9574

VL - 111

SP - 535

EP - 537

JO - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

JF - South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

IS - 6

ER -

Recommendations for the diagnosis and management of vaccine-induced immune thrombotic thrombocytopenia

Abstract

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