TY - JOUR
T1 - Recommendations for the surveillance of cancer-related fatigue in childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group
AU - Christen, Salome
AU - Roser, Katharina
AU - Mulder, Renée L.
AU - Ilic, Anica
AU - Lie, Hanne C.
AU - Loonen, Jacqueline J.
AU - Mellblom, Anneli V.
AU - Kremer, Leontien C. M.
AU - Hudson, Melissa M.
AU - Constine, Louis S.
AU - Skinner, Roderick
AU - Scheinemann, Katrin
AU - on behalf of the IGHG psychological late effects group
AU - Gilleland Marchak, Jordan
AU - Michel, Gisela
N1 - Funding Information: We thank the survivor representatives Jaap den Hartogh (The Netherlands), Zuzana Tom??ikov? (Switzerland), and Carina Schneider (Austria) from CCI Europe, and Clarissa Schilstra (Australia) for their critical and valuable appraisal of the recommendations. Funding Information: This work was supported by the Krebsliga Zentralschweiz, the Swiss National Science Foundation (Grant No. 10001C_182129/1 and 100019_153268/1), and the European Union’s Seventh Framework Programme for research, technological development, and demonstration, under grant agreement number 257505. The University of Lucerne research committee (FoKo) ( https://www.unilu.ch/en/research/university-of-lucerne-funding/research-committee/ ) and the Dept Health Science and Medicine of the University of Lucerne support the open access publication. Publisher Copyright: © 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Purpose: Cancer-related fatigue (CRF) negatively affects the lives of childhood, adolescent, and young adult (CAYA) cancer survivors. We aimed to provide an evidence-based clinical practice guideline (CPG) with internationally harmonized CRF surveillance recommendations for CAYA cancer survivors diagnosed < 30 years. Methods: This CPG was developed by a multidisciplinary panel under the umbrella of the International Late Effects of Childhood Cancer Guideline Harmonization Group. After evaluating concordances and discordances of four existing CPGs, we performed systematic literature searches. We screened articles for eligibility, assessed quality, extracted, and summarized the data from included articles. We formulated recommendations based on the evidence and clinical judgment. Results: Of 3647 articles identified, 70 articles from 14 countries were included. The prevalence of CRF in CAYA cancer survivors ranged from 10–85%. We recommend that healthcare providers are aware of the risk of CRF, implement regular screening with validated measures, and recommend effective interventions to fatigued survivors. Conclusions: A considerable proportion of CAYA cancer survivors suffers from CRF even years after the end of treatment. Implications for Cancer Survivors: We recommend that healthcare providers adopt regular screening to detect and treat CRF early and positively influence survivors’ health and quality of life.
AB - Purpose: Cancer-related fatigue (CRF) negatively affects the lives of childhood, adolescent, and young adult (CAYA) cancer survivors. We aimed to provide an evidence-based clinical practice guideline (CPG) with internationally harmonized CRF surveillance recommendations for CAYA cancer survivors diagnosed < 30 years. Methods: This CPG was developed by a multidisciplinary panel under the umbrella of the International Late Effects of Childhood Cancer Guideline Harmonization Group. After evaluating concordances and discordances of four existing CPGs, we performed systematic literature searches. We screened articles for eligibility, assessed quality, extracted, and summarized the data from included articles. We formulated recommendations based on the evidence and clinical judgment. Results: Of 3647 articles identified, 70 articles from 14 countries were included. The prevalence of CRF in CAYA cancer survivors ranged from 10–85%. We recommend that healthcare providers are aware of the risk of CRF, implement regular screening with validated measures, and recommend effective interventions to fatigued survivors. Conclusions: A considerable proportion of CAYA cancer survivors suffers from CRF even years after the end of treatment. Implications for Cancer Survivors: We recommend that healthcare providers adopt regular screening to detect and treat CRF early and positively influence survivors’ health and quality of life.
KW - Cancer-related fatigue
KW - Childhood, adolescent, and young adult cancer
KW - Evidence-based guidelines
KW - Late effects
KW - Surveillance
KW - Survivors
UR - http://www.scopus.com/inward/record.url?scp=85089785099&partnerID=8YFLogxK
U2 - https://doi.org/10.1007/s11764-020-00904-9
DO - https://doi.org/10.1007/s11764-020-00904-9
M3 - Review article
C2 - 32839902
SN - 1932-2259
VL - 14
SP - 923
EP - 938
JO - Journal of Cancer Survivorship
JF - Journal of Cancer Survivorship
IS - 6
ER -