TY - JOUR
T1 - Reevaluating the FDA's warning against the use of probiotics in preterm neonates
T2 - A societal statement by ESPGHAN and EFCNI
AU - van den Akker, Chris H P
AU - Embleton, Nicholas D
AU - Lapillonne, Alexandre
AU - Mihatsch, Walter A
AU - Salvatore, Silva
AU - Canani, Roberto B
AU - Dinleyici, Ener C
AU - Domellöf, Magnus
AU - Guarino, Alfredo
AU - Gutiérrez-Castrellón, Pedro
AU - Hojsak, Iva
AU - Indrio, Flavia
AU - Mosca, Alexis
AU - Orel, Rok
AU - van Goudoever, Johannes Hans B
AU - Weizman, Zvi
AU - Mader, Silke
AU - Zimmermann, Luc J I
AU - Shamir, Raanan
AU - Vandenplas, Yvan
AU - Szajewska, Hania
N1 - Publisher Copyright: © 2024 The Authors. Journal of Pediatric Gastroenterology and Nutrition published by Wiley Periodicals LLC on behalf of European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
PY - 2024/4/4
Y1 - 2024/4/4
N2 - The recent advisory issued by the United States Food and Drug Administration, cautioning against the routine administration of probiotics in preterm neonates, has sparked a lively debate within the scientific community. This commentary presents a perspective from members of the Special Interest Group on Gut Microbiota and Modifications within the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and other authors who contributed to the ESPGHAN position paper on probiotics for preterm infants, as well as representatives from the European Foundation for the Care of Newborn Infants. We advocate for a more nuanced and supportive approach to the use of certain probiotics in this vulnerable population, balancing the demonstrated benefits and risks.
AB - The recent advisory issued by the United States Food and Drug Administration, cautioning against the routine administration of probiotics in preterm neonates, has sparked a lively debate within the scientific community. This commentary presents a perspective from members of the Special Interest Group on Gut Microbiota and Modifications within the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and other authors who contributed to the ESPGHAN position paper on probiotics for preterm infants, as well as representatives from the European Foundation for the Care of Newborn Infants. We advocate for a more nuanced and supportive approach to the use of certain probiotics in this vulnerable population, balancing the demonstrated benefits and risks.
KW - live biotherapeutic product
KW - necrotizing enterocolitis
KW - premature infants
KW - probiotic drug
KW - probiotic sepsis
UR - http://www.scopus.com/inward/record.url?scp=85190274542&partnerID=8YFLogxK
U2 - 10.1002/jpn3.12204
DO - 10.1002/jpn3.12204
M3 - Article
C2 - 38572770
SN - 0277-2116
JO - Journal of pediatric gastroenterology and nutrition
JF - Journal of pediatric gastroenterology and nutrition
ER -