TY - JOUR
T1 - Refractive index measurement using single fiber reflectance spectroscopy
AU - Zhang, Xu U.
AU - Faber, Dirk J.
AU - Post, Anouk L.
AU - van Leeuwen, Ton G.
AU - Sterenborg, Henricus J. C. M.
N1 - © 2019 The Authors. Journal of Biophotonics published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - A method using single fiber reflectance spectroscopy to measure the refractive indices of transparent and turbid media over a broad wavelength range is presented and tested. For transparent liquid samples, the accuracy is within 0.2%, and the accuracy increases with increasing wavelength. For liquid turbid media, the accuracy is within 0.3% and increases with decreasing wavelength. For solid turbid samples, such as human skin, the accuracy critically depends on the optical contact between the fiber and sample surface. It is demonstrated that this technique has the potential to measure refractive indices of biological tissue in vivo.
AB - A method using single fiber reflectance spectroscopy to measure the refractive indices of transparent and turbid media over a broad wavelength range is presented and tested. For transparent liquid samples, the accuracy is within 0.2%, and the accuracy increases with increasing wavelength. For liquid turbid media, the accuracy is within 0.3% and increases with decreasing wavelength. For solid turbid samples, such as human skin, the accuracy critically depends on the optical contact between the fiber and sample surface. It is demonstrated that this technique has the potential to measure refractive indices of biological tissue in vivo.
UR - http://www.scopus.com/inward/record.url?scp=85063779917&partnerID=8YFLogxK
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85063779917&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30908898
U2 - https://doi.org/10.1002/jbio.201900019
DO - https://doi.org/10.1002/jbio.201900019
M3 - Article
C2 - 30908898
SN - 1864-063X
VL - 12
SP - e201900019
JO - Journal of Biophotonics
JF - Journal of Biophotonics
IS - 7
M1 - e201900019
ER -