Regulation of hematopoietic cell function by protein tyrosine kinase-encoding oncogenes, a review

C. J. Punt

doi:https://doi.org/10.1016/0145-2126(92)90001-N

Regulation of hematopoietic cell function by protein tyrosine kinase-encoding oncogenes, a review

C. J. Punt

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Research output: Contribution to journal › Review article › Academic › peer-review

10 Citations (Scopus)

Abstract

Tyrosine phosphorylation of proteins by protein tyrosine kinases (PTKs) is an important mechanism in the regulation of various cellular processes such as proliferation, differentiation, and transformation. Accumulating data implicate PTKs as essential intermediates in the transduction of extracellular signals to the interior of the cell. This review summarizes the mechanism of action of PTKs from the major subclasses and the involvement of PTK-encoding oncogenes in the regulation of hematopoietic cell function

Original language	English
Pages (from-to)	551-559
Journal	Leukemia research
Volume	16
Issue number	6-7
DOIs	https://doi.org/10.1016/0145-2126(92)90001-N
Publication status	Published - 1992

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https://doi.org/10.1016/0145-2126(92)90001-N

Cite this

@article{59d17c67ae394e42bd2980ed149ad96c,

title = "Regulation of hematopoietic cell function by protein tyrosine kinase-encoding oncogenes, a review",

abstract = "Tyrosine phosphorylation of proteins by protein tyrosine kinases (PTKs) is an important mechanism in the regulation of various cellular processes such as proliferation, differentiation, and transformation. Accumulating data implicate PTKs as essential intermediates in the transduction of extracellular signals to the interior of the cell. This review summarizes the mechanism of action of PTKs from the major subclasses and the involvement of PTK-encoding oncogenes in the regulation of hematopoietic cell function",

author = "Punt, {C. J.}",

year = "1992",

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language = "English",

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journal = "Leukemia research",

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TY - JOUR

T1 - Regulation of hematopoietic cell function by protein tyrosine kinase-encoding oncogenes, a review

AU - Punt, C. J.

PY - 1992

Y1 - 1992

N2 - Tyrosine phosphorylation of proteins by protein tyrosine kinases (PTKs) is an important mechanism in the regulation of various cellular processes such as proliferation, differentiation, and transformation. Accumulating data implicate PTKs as essential intermediates in the transduction of extracellular signals to the interior of the cell. This review summarizes the mechanism of action of PTKs from the major subclasses and the involvement of PTK-encoding oncogenes in the regulation of hematopoietic cell function

AB - Tyrosine phosphorylation of proteins by protein tyrosine kinases (PTKs) is an important mechanism in the regulation of various cellular processes such as proliferation, differentiation, and transformation. Accumulating data implicate PTKs as essential intermediates in the transduction of extracellular signals to the interior of the cell. This review summarizes the mechanism of action of PTKs from the major subclasses and the involvement of PTK-encoding oncogenes in the regulation of hematopoietic cell function

U2 - https://doi.org/10.1016/0145-2126(92)90001-N

DO - https://doi.org/10.1016/0145-2126(92)90001-N

M3 - Review article

C2 - 1635374

SN - 0145-2126

VL - 16

SP - 551

EP - 559

JO - Leukemia research

JF - Leukemia research

IS - 6-7

ER -