Reliability and responsiveness of the Juvenile Arthritis MRI Scoring (JAMRIS) system for the knee

Robert Hemke; Marion A J van Rossum; Mira van Veenendaal; Maaike P Terra; Eline E Deurloo; Milko C de Jonge; J Merlijn van den Berg; Koert M Dolman; Taco W Kuijpers; Mario Maas

doi:https://doi.org/10.1007/s00330-012-2684-y

Reliability and responsiveness of the Juvenile Arthritis MRI Scoring (JAMRIS) system for the knee

Robert Hemke, Marion A J van Rossum, Mira van Veenendaal, Maaike P Terra, Eline E Deurloo, Milko C de Jonge, J Merlijn van den Berg, Koert M Dolman, Taco W Kuijpers, Mario Maas

Research output: Contribution to journal › Article › Academic › peer-review

72 Citations (Scopus)

Abstract

OBJECTIVES: To assess the reliability and responsiveness of a new Juvenile Arthritis MRI Scoring (JAMRIS) system for evaluating disease activity of the knee.

METHODS: Twenty-five juvenile idiopathic arthritis (JIA) patients with clinical knee involvement were studied using open-bore 1-T MRI. MRI features of synovial hypertrophy, bone marrow changes, cartilage lesions and bone erosions were independently scored by five readers using the JAMRIS system. In addition, the JAMRIS system was determined to be a follow-up parameter by two readers to evaluate the response to therapy in 15 consecutive JIA patients.

RESULTS: Inter-reader (ICCs 0.86-0.95) and intra-reader reliability (ICCs 0.92-1.00) for the scoring of JAMRIS features was good. Reliability of the actual scores and changes in scores over time was good for all items: ICCs 0.89-1.00, 0.87-1.00, respectively. Concerning therapy response, the mean synovial hypertrophy scores decreased significantly (mean 1.1 point; P < 0.001, SRM = -0.65). No change was observed with respect to bone marrow change, cartilage lesion and bone erosion scores.

CONCLUSIONS: The JAMRIS proved to be a simple and highly reliable assessment score in the evaluation of JIA disease activity of the knee. The JAMRIS system may serve as an objective and accurate outcome measure in future research and clinical trials.

Original language	English
Pages (from-to)	1075-83
Number of pages	9
Journal	European Radiology
Volume	23
Issue number	4
DOIs	https://doi.org/10.1007/s00330-012-2684-y
Publication status	Published - Apr 2013

Keywords

Adolescent
Algorithms
Arthritis, Juvenile/pathology
Child
Female
Humans
Image Enhancement/methods
Image Interpretation, Computer-Assisted/methods
Magnetic Resonance Imaging/methods
Male
Netherlands
Osteoarthritis, Knee/pathology
Reproducibility of Results
Sensitivity and Specificity
Severity of Illness Index

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https://doi.org/10.1007/s00330-012-2684-y

Cite this

@article{4d487636594c4dfc8e248aa4259ceeea,

title = "Reliability and responsiveness of the Juvenile Arthritis MRI Scoring (JAMRIS) system for the knee",

abstract = "OBJECTIVES: To assess the reliability and responsiveness of a new Juvenile Arthritis MRI Scoring (JAMRIS) system for evaluating disease activity of the knee.METHODS: Twenty-five juvenile idiopathic arthritis (JIA) patients with clinical knee involvement were studied using open-bore 1-T MRI. MRI features of synovial hypertrophy, bone marrow changes, cartilage lesions and bone erosions were independently scored by five readers using the JAMRIS system. In addition, the JAMRIS system was determined to be a follow-up parameter by two readers to evaluate the response to therapy in 15 consecutive JIA patients.RESULTS: Inter-reader (ICCs 0.86-0.95) and intra-reader reliability (ICCs 0.92-1.00) for the scoring of JAMRIS features was good. Reliability of the actual scores and changes in scores over time was good for all items: ICCs 0.89-1.00, 0.87-1.00, respectively. Concerning therapy response, the mean synovial hypertrophy scores decreased significantly (mean 1.1 point; P < 0.001, SRM = -0.65). No change was observed with respect to bone marrow change, cartilage lesion and bone erosion scores.CONCLUSIONS: The JAMRIS proved to be a simple and highly reliable assessment score in the evaluation of JIA disease activity of the knee. The JAMRIS system may serve as an objective and accurate outcome measure in future research and clinical trials.",

keywords = "Adolescent, Algorithms, Arthritis, Juvenile/pathology, Child, Female, Humans, Image Enhancement/methods, Image Interpretation, Computer-Assisted/methods, Magnetic Resonance Imaging/methods, Male, Netherlands, Osteoarthritis, Knee/pathology, Reproducibility of Results, Sensitivity and Specificity, Severity of Illness Index",

author = "Robert Hemke and {van Rossum}, {Marion A J} and {van Veenendaal}, Mira and Terra, {Maaike P} and Deurloo, {Eline E} and {de Jonge}, {Milko C} and {van den Berg}, {J Merlijn} and Dolman, {Koert M} and Kuijpers, {Taco W} and Mario Maas",

year = "2013",

month = apr,

doi = "https://doi.org/10.1007/s00330-012-2684-y",

language = "English",

volume = "23",

pages = "1075--83",

journal = "European Radiology",

issn = "0938-7994",

publisher = "Springer Verlag",

number = "4",

}

TY - JOUR

T1 - Reliability and responsiveness of the Juvenile Arthritis MRI Scoring (JAMRIS) system for the knee

AU - Hemke, Robert

AU - van Rossum, Marion A J

AU - van Veenendaal, Mira

AU - Terra, Maaike P

AU - Deurloo, Eline E

AU - de Jonge, Milko C

AU - van den Berg, J Merlijn

AU - Dolman, Koert M

AU - Kuijpers, Taco W

AU - Maas, Mario

PY - 2013/4

Y1 - 2013/4

N2 - OBJECTIVES: To assess the reliability and responsiveness of a new Juvenile Arthritis MRI Scoring (JAMRIS) system for evaluating disease activity of the knee.METHODS: Twenty-five juvenile idiopathic arthritis (JIA) patients with clinical knee involvement were studied using open-bore 1-T MRI. MRI features of synovial hypertrophy, bone marrow changes, cartilage lesions and bone erosions were independently scored by five readers using the JAMRIS system. In addition, the JAMRIS system was determined to be a follow-up parameter by two readers to evaluate the response to therapy in 15 consecutive JIA patients.RESULTS: Inter-reader (ICCs 0.86-0.95) and intra-reader reliability (ICCs 0.92-1.00) for the scoring of JAMRIS features was good. Reliability of the actual scores and changes in scores over time was good for all items: ICCs 0.89-1.00, 0.87-1.00, respectively. Concerning therapy response, the mean synovial hypertrophy scores decreased significantly (mean 1.1 point; P < 0.001, SRM = -0.65). No change was observed with respect to bone marrow change, cartilage lesion and bone erosion scores.CONCLUSIONS: The JAMRIS proved to be a simple and highly reliable assessment score in the evaluation of JIA disease activity of the knee. The JAMRIS system may serve as an objective and accurate outcome measure in future research and clinical trials.

AB - OBJECTIVES: To assess the reliability and responsiveness of a new Juvenile Arthritis MRI Scoring (JAMRIS) system for evaluating disease activity of the knee.METHODS: Twenty-five juvenile idiopathic arthritis (JIA) patients with clinical knee involvement were studied using open-bore 1-T MRI. MRI features of synovial hypertrophy, bone marrow changes, cartilage lesions and bone erosions were independently scored by five readers using the JAMRIS system. In addition, the JAMRIS system was determined to be a follow-up parameter by two readers to evaluate the response to therapy in 15 consecutive JIA patients.RESULTS: Inter-reader (ICCs 0.86-0.95) and intra-reader reliability (ICCs 0.92-1.00) for the scoring of JAMRIS features was good. Reliability of the actual scores and changes in scores over time was good for all items: ICCs 0.89-1.00, 0.87-1.00, respectively. Concerning therapy response, the mean synovial hypertrophy scores decreased significantly (mean 1.1 point; P < 0.001, SRM = -0.65). No change was observed with respect to bone marrow change, cartilage lesion and bone erosion scores.CONCLUSIONS: The JAMRIS proved to be a simple and highly reliable assessment score in the evaluation of JIA disease activity of the knee. The JAMRIS system may serve as an objective and accurate outcome measure in future research and clinical trials.

KW - Adolescent

KW - Algorithms

KW - Arthritis, Juvenile/pathology

KW - Child

KW - Female

KW - Humans

KW - Image Enhancement/methods

KW - Image Interpretation, Computer-Assisted/methods

KW - Magnetic Resonance Imaging/methods

KW - Male

KW - Netherlands

KW - Osteoarthritis, Knee/pathology

KW - Reproducibility of Results

KW - Sensitivity and Specificity

KW - Severity of Illness Index

U2 - https://doi.org/10.1007/s00330-012-2684-y

DO - https://doi.org/10.1007/s00330-012-2684-y

M3 - Article

C2 - 23085866

SN - 0938-7994

VL - 23

SP - 1075

EP - 1083

JO - European Radiology

JF - European Radiology

IS - 4

ER -